Awareness, Knowledge, and Vaccine Acceptability of Herpes Zoster in Korea: A Multicenter Survey of 607 Patients
2
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Background: Herpes zoster (HZ) infection can significantly impair the quality of life of the affected individuals, and its treatment imposes a considerable cost burden on the health-care system and on society at large. However, there is little information on the perception of this disease and the acceptability of vaccines in Korea. Objective: The aim of this study is to determine the awareness of HZ and its vaccine, and to identify factors associated with the acceptability of the HZ vaccine among outpatients of dermatology clinics. Methods: A questionnaire-based survey was conducted on 607 outpatients who visited the dermatologic clinics. Results: The responses of the patients revealed a high awareness of HZ (85.4%) but a relatively low knowledge about HZ and its vaccine (42.3%). The HZ vaccination rate among patients aged ≥50 years was 9%. A history of HZ infection, being older, and greater knowledge about HZ and its vaccine were associated with a higher HZ vaccine acceptability. Of those who had not been vaccinated, 58.3% were interested in receiving the vaccine. The most frequent reason for this interest was “severe sequelae,” followed by “knowing someone who has HZ” and “recommendation from a doctor.” High cost was the most common reason for unwillingness to receive the vaccination. Conclusion: Despite a high awareness of HZ, vaccine acceptability was extremely low among this study cohort. Vaccination acceptability would be improved by encouraging doctors to educate elderly patients about the disease and the availability of vaccination, and by the provision of insurance coverage for HZ vaccination.
Abstract
Background: Herpes zoster (HZ) infection can significantly impair the quality of life of the affected individuals, and its treatment imposes a considerable cost burden on the health-care system and on society at large. However, there is little information on the perception of this disease and the acceptability of vaccines in Korea. Objective: The aim of this study is to determine the awareness of HZ and its vaccine, and to identify factors associated with the acceptability of the HZ vaccine among outpatients of dermatology clinics. Methods: A questionnaire-based survey was conducted on 607 outpatients who visited the dermatologic clinics. Results: The responses of the patients revealed a high awareness of HZ (85.4%) but a relatively low knowledge about HZ and its vaccine (42.3%). The HZ vaccination rate among patients aged ≥50 years was 9%. A history of HZ infection, being older, and greater knowledge about HZ and its vaccine were associated with a higher HZ vaccine acceptability. Of those who had not been vaccinated, 58.3% were interested in receiving the vaccine. The most frequent reason for this interest was “severe sequelae,” followed by “knowing someone who has HZ” and “recommendation from a doctor.” High cost was the most common reason for unwillingness to receive the vaccination. Conclusion: Despite a high awareness of HZ, vaccine acceptability was extremely low among this study cohort. Vaccination acceptability would be improved by encouraging doctors to educate elderly patients about the disease and the availability of vaccination, and by the provision of insurance coverage for HZ vaccination.
참고문헌 (22)
- Langan SM, "Herpes zoster vaccine effectiveness against incident herpes zoster and post-herpetic neuralgia in an older US population: a cohort study", PLoS Med, 10, pp.e1001420~ (2013)
- Oxman MN, "A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults", N Engl J Med, 352, pp.2271~2284 (2005)
- Gilden DH, "Varicella-zoster virus vaccine--grown-ups need it, too", N Engl J Med, 352, pp.2344~2346 (2005)
- Hurley LP, "National survey of primary care physicians regarding herpes zoster and the herpes zoster vaccine", J Infect Dis, 197(Suppl 2), pp.S216~S223 (2008)
- "ZOSTAVAX Product Information" (2013)[URL]
- Weinberg JM, "Herpes zoster: epidemiology, natural history, and common complications", J Am Acad Dermatol, 57(6 Suppl), pp.S130~S135 (2007)
- Brisson M, "Epidemiology of varicella zoster virus infection in Canada and the United Kingdom", Epidemiol Infect, 127, pp.305~314 (2001)
- Russell ML, "Secular trends in the epidemiology of shingles in Alberta", Epidemiol Infect, 135, pp.908~913 (2007)
- Pérez-Farinós N, "Varicella and herpes zoster in Madrid, based on the Sentinel General Practitioner Network: 1997-2004", BMC Infect Dis, 7, pp.59~ (2007)
- Chao DY, "The incidence of varicella and herpes zoster in Taiwan during a period of increasing varicella vaccine coverage, 2000-2008", Epidemiol Infect, 140, pp.1131~1140 (2012)
- Choi WS, "Disease burden of herpes zoster in Korea", J Clin Virol, 47, pp.325~329 (2010)
- Toyama N, "Epidemiology of herpes zoster and its relationship to varicella in Japan: a 10-year survey of 48,388herpes zoster cases in Miyazaki prefecture", J Med Virol, 81, pp.2053~2058 (2009)
- Drolet M, "The impact of herpes zoster and posthe rpetic neuralgia on health-related quality of life: a prospective study", CMAJ, 182, pp.1731~1736 (2010)
- Chidiac C, "Characteristics of patients with herpes zoster on presentation to practitioners in France", Clin Infect Dis, 33, pp.62~69 (2001)
- Oster G, "Pain, medication use, and health-related quality of life in older persons with postherpetic neuralgia: results from a population-based survey", J Pain, 6, pp.356~363 (2005)
- Weinke T, "Impact of herpes zoster and post-herpetic neuralgia on patients' quality of life: a patient-reported outcomes survey", Z Gesundh Wiss, 18, pp.367~374 (2010)
- Schmader K, "The epidemiological, clinical, and pathological rationale for the herpes zoster vaccine", J Infect Dis, 197(Suppl 2), pp.S207~S215 (2008)
- Bouhassira D, "Patient perspective on herpes zoster and its complications: an observational prospective study in patients aged over 50 years in general practice", Pain, 153, pp.342~349 (2012)
- Javed S, "Herpes zoster vaccine awareness among people ≥50 years of age and its implications on immunization", Dermatol Online J, 18, pp.2~ (2012)
- Lee TJ, "Herpes zoster knowledge, prevalence, and vaccination rate by race", J Am Board Fam Med, 26, pp.45~51 (2013)
- Kawai K, "Cost-effectiveness of vaccination against herpes zoster and postherpetic neuralgia: a critical review", Vaccine, 32, pp.1645~1653 (2014)