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A Case of Intradermal Melanocytic Nevus with Ossification (Nevus of Nanta)

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초록

A 49-year-old woman presented with a 30-year history of asymptomatic plaque on her right temple. The histological examination revealed nests of nevus cells throughout the entire dermis. Bony spicules were seen just beneath the nevus cell nests in the lower dermis. Cutaneous ossification is an unusual event. Herein, we present a case of intradermal melanocytic nevus with unusual ossification (nevus of Nanta). To the best of our knowledge, this is the first such case report in the Korean literature. (Ann Dermatol(Seoul) 20(4) 197∼199, 2008)

Abstract

A 49-year-old woman presented with a 30-year history of asymptomatic plaque on her right temple. The histological examination revealed nests of nevus cells throughout the entire dermis. Bony spicules were seen just beneath the nevus cell nests in the lower dermis. Cutaneous ossification is an unusual event. Herein, we present a case of intradermal melanocytic nevus with unusual ossification (nevus of Nanta). To the best of our knowledge, this is the first such case report in the Korean literature. (Ann Dermatol(Seoul) 20(4) 197∼199, 2008)

참고문헌 (9)

  1. Burgdorf W, "Cutaneous osteomas: a clinical and histopathologic review", Arch Dermato Res, 260, pp.121~135 (1977)
  2. Elder DE, "Lever's Histopathology of the skin", pp.1089~1093 (2005), Lippincott Williams & Wilkins
  3. Moulin G, "Pigmented nevus and cutaneous ossifications. Apropos of 125 cases of osteonevi", Ann Dermatol Venereol, 118, pp.199~204 (1991)
  4. Kanitakis J, "Mummified ossified melanocytic naevus", Eur J Dermatol, 10, pp.466~467 (2000)
  5. Orlow SJ, "Skin and bones. II", J Am Acad Dermatol, 24, pp.447~462 (1991)
  6. Conlin PA, "Osteomas of the skin revisited: a clinicopathologic review of 74 cases", Am J Dermatopathol, 24, pp.479~483 (2002)
  7. Sasaki S, "Osteo-nevus of Nanta: a case report and review of the Japanese literature", J Dermatol, 26, pp.183~188 (1999)
  8. Keida T, "Transforming growth factor beta and connective tissue growth factor are involved in the evolution of nevus of Nanta", J Dermatol, 32, pp.442~445 (2005)
  9. Culver W, "Malignant melanoma arising in a nevus of Nanta", J Cutan Pathol, 20, pp.375~377 (1993)

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