A Case of Eccrine Spiradenoma in a Patient with Neurofibromatosis
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Neurofibromatosis is a systemic hereditary disorder with varied manifestations in bone, soft tissue, the nervous system and skin. Cutaneous manifestations of neurofibromatosis are characterized by café-au-lait macules, multiple neurofibromas,Lisch nodules and intertriginous freckling. Some benign or malignant tumors such as juvenile xanthogranuloma,pheochromocytoma, and malignant melanoma can accompany neurofibromatosis. But, in the English literature,no case of eccrine spiradenoma associated with neurofibromatosis has been reported. Eccrine spiradenoma is a benign uncommon neoplasm of skin adnexa. It presents as a painful, slow-growing and solitary nodule on the head or upper trunk. Here, we report a rare case of eccrine spiradenoma in a patient with neurofibromatosis. (Ann Dermatol 22(2) 191∼193, 2010
Abstract
Neurofibromatosis is a systemic hereditary disorder with varied manifestations in bone, soft tissue, the nervous system and skin. Cutaneous manifestations of neurofibromatosis are characterized by café-au-lait macules, multiple neurofibromas,Lisch nodules and intertriginous freckling. Some benign or malignant tumors such as juvenile xanthogranuloma,pheochromocytoma, and malignant melanoma can accompany neurofibromatosis. But, in the English literature,no case of eccrine spiradenoma associated with neurofibromatosis has been reported. Eccrine spiradenoma is a benign uncommon neoplasm of skin adnexa. It presents as a painful, slow-growing and solitary nodule on the head or upper trunk. Here, we report a rare case of eccrine spiradenoma in a patient with neurofibromatosis. (Ann Dermatol 22(2) 191∼193, 2010
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