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A Case of Clear Cell Eccrine Porocarcinoma

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초록

Eccrine porocarcinoma (EP) is a rare malignant tumor arising from the intraepidermal eccrine duct. The tumor cells frequently contain glycogen, but prominent clear cell changes in EP are rarely reported. A 78-year-old woman presented with a slightly pruritic, erythematous, verrucous plaque on her left thigh. Histopathological examination revealed intraepidermal tumor cell nests composed of small basaloid cells and duct-like structures lined by periodic acid-Schiff (PAS)-positive cuticles. Besides the typical findings of EP, clear cell changes were predominantly observed in the tumor cell aggregations. Herein we report a case of the clear cell variant of EP rarely reported in previous literature. (Ann Dermatol 22(3) 330∼332, 2010)

Abstract

Eccrine porocarcinoma (EP) is a rare malignant tumor arising from the intraepidermal eccrine duct. The tumor cells frequently contain glycogen, but prominent clear cell changes in EP are rarely reported. A 78-year-old woman presented with a slightly pruritic, erythematous, verrucous plaque on her left thigh. Histopathological examination revealed intraepidermal tumor cell nests composed of small basaloid cells and duct-like structures lined by periodic acid-Schiff (PAS)-positive cuticles. Besides the typical findings of EP, clear cell changes were predominantly observed in the tumor cell aggregations. Herein we report a case of the clear cell variant of EP rarely reported in previous literature. (Ann Dermatol 22(3) 330∼332, 2010)

참고문헌 (6)

  1. Rutten A, "Clear-cell porocarcinoma in situ:a cytologic variant of porocarcinoma in situ", Am J Dermatopathol, 24, pp.67~71 (2002)
  2. Pinkus H, "Epidermotropic eccrine carcinoma.A case combining features of eccrine poroma and Paget's dermatosis", Arch Dermatol, 88, pp.597~606 (1963)
  3. Robson A, "Eccrine porocarcinoma(malignant eccrine poroma):a clinicopathologic study of 69 cases", Am J Surg Pathol, 25, pp.710~720 (2001)
  4. Requena L, "Clear-cell porocarcinoma:another cutaneous marker of diabetes mellitus", Am J Dermatopathol, 19, pp.540~544 (1997)
  5. Saitoh A, "Clear cells of eccrine glands in a patient with clear cell syringoma associated with diabetes mellitus", Am J Dermatopathol, 15, pp.166~168 (1993)
  6. Wong TY, "Clear cell eccrine carcinomas of the skin.A clinicopathologic study of nine patients", Cancer, 73, pp.1631~1643 (1994)

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