알츠하이머병에서 동시에 증상이 나타난Pisa 증후군과 정상압 수두증
Pisa Syndrome in a Patient with Alzheimer’s Disease and Concomitant Normal Pressure Hydrocephalus: A Case Report
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Extrapyramidal symptoms are common in patients with advanced Alzheimer’s disease and have various etiologies. We report a 65-year-old man with probable Alzheimer’s disease (AD) who concomitantly developed Pisa syndrome, ataxic gait, postural instability and voiding difficulty. Pisa syndrome improved after the discontinuation of acetylcholinesterase inhibitor (AchEI) and antipsychotics. However his ataxic gait and voiding symptoms persisted. A ventriculo-peritoneal shunt operation eliminated the symptoms except for cognition. We report Pisa syndrome in a patient with Alzheimer’s disease and concomitant normal pressure hydrocephalus.
Abstract
Extrapyramidal symptoms are common in patients with advanced Alzheimer’s disease and have various etiologies. We report a 65-year-old man with probable Alzheimer’s disease (AD) who concomitantly developed Pisa syndrome, ataxic gait, postural instability and voiding difficulty. Pisa syndrome improved after the discontinuation of acetylcholinesterase inhibitor (AchEI) and antipsychotics. However his ataxic gait and voiding symptoms persisted. A ventriculo-peritoneal shunt operation eliminated the symptoms except for cognition. We report Pisa syndrome in a patient with Alzheimer’s disease and concomitant normal pressure hydrocephalus.
참고문헌 (11)
- Canadian Study of Health and Aging Working Group, "Canadian Study of Health and Aging: study methods and prevalence of dementia", Can Med Assoc J, 150, pp.899~912 (1994)
- Mario FM, "Dementia: a clinical approach. 3rd ed" (2003), Butterworth & Heinemann
- Ekbom K, "New dystonic syndrome associatedwit butyrophenone therapy", Z Neurol, 202, pp.94~103 (1972)
- Suzuki T, "Clinical characteristics of the Pisa syndrome", Acta Psychiatr Scand, 82, pp.454~457 (1990)
- Cossu G, "Reversible Pisa syndrome(Pleurothotonus) due to the cholinesterase inhibitor galantamine: case report", Mov Disord, 19, pp.1243~1244 (2004)
- Kwak YT, "Relation between cholinesterase inhibitor and Pisa syndrome", Lancet, 355(9222), pp.2222~ (2000)
- Hakim S, "The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure: observations on cerebrospinal fluid hydrodynamics", J Neurol Sci, 2, pp.307~327 (1965)
- Gjerris F, "Pathophysiology of the CSF circulation In Neurosurgery-the scientific basis of clinical practice", pp.147~168 (2000), Blackwell Science
- Golomb J, "Alzheimer’s disease comorbidity in normal pressure hydrocephalus: prevalence and shunt response", J Neurol Neurosurg Psychiatry, 6, pp.778~781 (2000)
- Silverberg GD, "Alzheimer’s disease, normal-pressure hydrocephalus, and senescent changes in CSF circulatory physiology: a hypothesis", Lancet Neurol, 8, pp.506~511 (2003)
- Baik JS, "Four cases of Pisa syndrome in risperidone therapy", J Korean Neurol Assoc, 18, pp.89~93 (2000)