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논문KCI 등재

뇌졸중 유사증상과 경련이 발생한 멜라스 환자의 혈관충혈과 교차소뇌기능해리

Vascular Hyperemia and Crossed Cerebellar Diaschisis in MELAS Patient Presented as Stroke-Like Episode and Seizure

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초록

Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) is one of the mitochondrial disorders that can present as a stroke-like episode or seizure. Although the pathophysiology of MELAS remains inconclusive, the main possibilities are thus far thought to be mitochondrial cytopathy and angiopathy. This case report describes a 61-year-old woman diagnosed with MELAS who presented simultaneously with vascular hyperemia and crossed cerebellar diaschisis.

Abstract

Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) is one of the mitochondrial disorders that can present as a stroke-like episode or seizure. Although the pathophysiology of MELAS remains inconclusive, the main possibilities are thus far thought to be mitochondrial cytopathy and angiopathy. This case report describes a 61-year-old woman diagnosed with MELAS who presented simultaneously with vascular hyperemia and crossed cerebellar diaschisis.

참고문헌 (10)

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  6. Tsuchiya K, "MELAS with prominent white matter gliosis and atrophy of the cerebellar granular layer: a clinical, genetic, and pathological study", Acta Neuropathol, 97, pp.520~524 (1999)
  7. Tsujikawa T, "Crossed cerebellar hyperperfusion after MELAS attack followed up by whole brain continuous arterial spin labeling perfusion imaging", Acta Radiol, 53, pp.220~222 (2012)
  8. Narla VV, "Diaschisis in Cerebral Mitochondrial Disorder", Clin Nucl Med, 33, pp.531~534 (2008)
  9. Ooiwa Y, "Cerebral blood flow in mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes", Stroke, 24, pp.304~309 (1993)
  10. Ito H, "Neuroimaging of stroke-like episodes in MELAS", Brain Dev, 33, pp.283~288 (2011)

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