글루포시네이트암모늄(glufosinate ammonium, BASTA ® ) 중독 후 발생한 뇌병증
Encephalopathy After Glufosinate Ammonium Intoxication
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초록
Glufosinate ammonium is the active ingredient in broad-spectrum contact herbicides such as BASTAⓇthat inhibits theactivity of glutamine synthetase, which is necessary for the production of the amino acid glutamine and for ammoniadetoxification. Complications of glufosinate ammonium intoxication include gastrointestinal symptoms, loss of consciousness,convulsions, memory impairment, respiratory failure, and cardiovascular instability. We report herein a case encephalopathy and reversible signal changes in the splenium of the corpus callosum, the bilateral corticospinal tracts,the hippocampi, and the cerebellar peduncles as seen in diffusion-weighted magnetic resonance imaging andfluid-attenuated inversion recovery images following BASTAⓇintoxication.
Abstract
Glufosinate ammonium is the active ingredient in broad-spectrum contact herbicides such as BASTAⓇthat inhibits theactivity of glutamine synthetase, which is necessary for the production of the amino acid glutamine and for ammoniadetoxification. Complications of glufosinate ammonium intoxication include gastrointestinal symptoms, loss of consciousness,convulsions, memory impairment, respiratory failure, and cardiovascular instability. We report herein a case encephalopathy and reversible signal changes in the splenium of the corpus callosum, the bilateral corticospinal tracts,the hippocampi, and the cerebellar peduncles as seen in diffusion-weighted magnetic resonance imaging andfluid-attenuated inversion recovery images following BASTAⓇintoxication.
참고문헌 (8)
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