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논문KCI 등재

경부후관절부 스테로이드 치료 후 발생한 비전형 적가역후뇌병증

Atypical Posterior Reversible Encephalopathy Syndrome after Cervical Facet Joint Steroid Injection

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초록

Posterior reversible encephalopathy syndrome (PRES) is characterized by headache, altered mental function, seizures,and loss of vision predominantly affecting the bilateral parieto-occipital area. Most cases of PRES are associated withhypertension, or use of immunosuppressants or cytotoxic drugs; associated brainstem and cerebellar lesions areuncommon. We report herein a case of PRES that developed in a patient after injecting a steroid for cervical painmanagement. The presence of a territorial lesion along the vertebral artery on the same side as the pain-managementprocedure suggests an association between injectable steroid suspension and PRES.

Abstract

Posterior reversible encephalopathy syndrome (PRES) is characterized by headache, altered mental function, seizures,and loss of vision predominantly affecting the bilateral parieto-occipital area. Most cases of PRES are associated withhypertension, or use of immunosuppressants or cytotoxic drugs; associated brainstem and cerebellar lesions areuncommon. We report herein a case of PRES that developed in a patient after injecting a steroid for cervical painmanagement. The presence of a territorial lesion along the vertebral artery on the same side as the pain-managementprocedure suggests an association between injectable steroid suspension and PRES.

참고문헌 (10)

  1. Fugate JE, "Posterior reversible encephalopathy syndrome: associated clinical and radiologic findings", Mayo Clin Proc, 85, pp.427~432 (2010)
  2. Liman TG, "The clin-ical and radiological spectrum of posterior reversible encephalopathy syndrome: the retrospective Berlin PRES study", J Neurol, 259, pp.155~164 (2012)
  3. Bartynski WS, "Posterior reversible encephalopathy syndrome, part 2:controversies surrounding pathophysiology of vasogenic edema", Am J Neuroradiol, 29, pp.1043~1049 (2008)
  4. Falco FJ, "Systematic review of the therapeutic effectiveness of cervical facet joint interventions: an update", Pain Physician, 15, pp.E839~E868 (2012)
  5. Edlow BL, "Posterior circulation stroke after C1-C2 intraarticular facet steroid in-jection: evidence for diffuse microvascular injury", Anesthesiology, 112, pp.1532~1535 (2010)
  6. Dawley JD, "Intra-arterial injection in the rat brain: evaluation of steroids used for trans-foraminal epidurals", Spine, 34, pp.1638~1643 (2009)
  7. Chang YS, "In vitro benzyl alcohol cytotoxicity: implications for intravitreal use of triamcinolone acetonide", Exp Eye Res, 86, pp.942~950 (2008)
  8. Russo VM, "The V (2)segment of the vertebral artery: anatomical considerations and surgi-cal implications", J Neurosurg Spine, 15, pp.610~619 (2011)
  9. Uchino A, "Vertebral artery variations at the C1-2 level diagnosed by magnetic resonance angiography", Neuroradiology, 54, pp.19~23 (2012)
  10. Liman TG, "Discharge status and in-hospital mortality in posterior reversible encephalopathy syndrome", Acta Neurol Scand, 130, pp.34~39 (2014)

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