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논문KCI 등재

행동변이형전두측두엽치매로 나타난 중증의 우측내경동맥협착증

Severe Right Internal Carotid Artery Stenosis Mimicking Behavioral Variant Frontotemporal Dementia

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주제분류신경과학

초록

Many kinds of degenerative, psychiatric, and cerebrovascular diseases can mimic behavioral variant frontotemporal dementia. We present a 73-year-old woman who presented with apathy, inappropriate social behavior, and persecutory delusion. A neuropsychological examination revealed frontal/executive dysfunction with relative sparing of episodic memory. Magnetic resonance imaging and F-18 fluorodeoxyglucose positron-emission tomography produced normal findings. However, magnetic resonance angiography revealed severe right internal carotid stenosis. After carotid stenting, her behavioral symptoms disappeared and did not recur during an 18-month follow-up.

Abstract

Many kinds of degenerative, psychiatric, and cerebrovascular diseases can mimic behavioral variant frontotemporal dementia. We present a 73-year-old woman who presented with apathy, inappropriate social behavior, and persecutory delusion. A neuropsychological examination revealed frontal/executive dysfunction with relative sparing of episodic memory. Magnetic resonance imaging and F-18 fluorodeoxyglucose positron-emission tomography produced normal findings. However, magnetic resonance angiography revealed severe right internal carotid stenosis. After carotid stenting, her behavioral symptoms disappeared and did not recur during an 18-month follow-up.

참고문헌 (10)

  1. Bang J, "Frontotemporal dementia", Lancet, 386, pp.1672~1682 (2015)
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  3. 윤별아, "Efect of Carotid Artery Stenting on Cognitive Function in Patients with Carotid Artery Stenosis: A Prospective, 3-Month-Follow-Up Study", Journal of Clinical Neurology, 11(2), pp.149~156 (2015), 대한신경과학회[DOI]
  4. Rascovsky K, "Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia", Brain, 134, pp.2456~2477 (2011)
  5. North American Symptomatic Carotid Endarterectomy Trial Collaborators, "Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis", N Engl J Med, 325, pp.445~453 (1991)
  6. Mendez MF, "Accuracy of the clinical evaluation for frontotemporal dementia", Arch Neurol, 64, pp.830~835 (2007)
  7. Johnson JK, "Baseline predictors of clinical progression among patients with dysexecutive mild cognitive impairment", Dement Geriatr Cogn Disord, 30, pp.344~351 (2010)
  8. Rosenberg PB, "Neuropsychiatric symptoms in MCI subtypes: the importance of executive dysfunction", Int J Geriatr Psychiatry, 26, pp.364~372 (2011)
  9. Mendiz OA, "Improvement in executive function after unilateral carotid artery stenting for severe asymptomatic stenosis", J Neurosurg, 116, pp.179~184 (2012)
  10. Harris JM, "Sensitivity and specificity of FTDC criteria for behavioral variant frontotemporal dementia", Neurology, 80, pp.1881~1887 (2013)

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