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Green Nail Syndrome Treated with the Application of Tobramycin Eye Drop

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Green nail syndrome (chromonychia) is a nail disorder characterizedby onycholysis and green-black discoloration ofthe nail bed. This condition is often associated with chronicparonychia. Pseudomonas aeruginosa is the most commonlyidentified organism in cultures from the affected area. Despite the various treatment options available, removal ofthe nail is still necessary in many cases. A 35-year-old manpresented with dark-greenish discoloration of the nail plateand onycholysis on the left thumbnail. He had been treatedwith oral antifungal and antibiotic agents for several months;however, the lesion showed no improvement. The diagnosisof green nail syndrome was established after a positivebacterial culture, and on the basis of the antibiotic sensitivitytest result, tobramycin eye drop (TobrexⓇ) was then prescribed. Three weeks later, the nail discoloration almostvanished but the onycholysis remained. Herein, we recommendthe application of tobramycin eye drop as an easy andsafe treatment option for green nail syndrome.

Abstract

Green nail syndrome (chromonychia) is a nail disorder characterizedby onycholysis and green-black discoloration ofthe nail bed. This condition is often associated with chronicparonychia. Pseudomonas aeruginosa is the most commonlyidentified organism in cultures from the affected area. Despite the various treatment options available, removal ofthe nail is still necessary in many cases. A 35-year-old manpresented with dark-greenish discoloration of the nail plateand onycholysis on the left thumbnail. He had been treatedwith oral antifungal and antibiotic agents for several months;however, the lesion showed no improvement. The diagnosisof green nail syndrome was established after a positivebacterial culture, and on the basis of the antibiotic sensitivitytest result, tobramycin eye drop (TobrexⓇ) was then prescribed. Three weeks later, the nail discoloration almostvanished but the onycholysis remained. Herein, we recommendthe application of tobramycin eye drop as an easy andsafe treatment option for green nail syndrome.

참고문헌 (10)

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  10. Brogden RN, "Tobramycin: a review of its antibacterial and pharmacokinetic properties and therapeutic use", Drugs, 12, pp.166~200 (1976)

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