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종양에 의한 색전과 동반된 혈전에 의한 뇌경색

Cerebral Infarction Caused by Direct Cardiac Tumor Emboli Mixed with Thrombus

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초록

Cerebral infarction in cancer patients is often caused by thrombosis due to hypercoagulability, and in some cases, caused by direct tumor embolism. We report the case of cerebral infarction due to direct tumor embolism mixed with thrombus. Biopsy of blood clots obtained during thrombectomy is important for diagnosis. If there is a high risk of thrombosis among cancer patients with cerebral infarction, the use of appropriate antithrombotic agents along with maintaining a certain level of platelets should be considered.

Abstract

Cerebral infarction in cancer patients is often caused by thrombosis due to hypercoagulability, and in some cases, caused by direct tumor embolism. We report the case of cerebral infarction due to direct tumor embolism mixed with thrombus. Biopsy of blood clots obtained during thrombectomy is important for diagnosis. If there is a high risk of thrombosis among cancer patients with cerebral infarction, the use of appropriate antithrombotic agents along with maintaining a certain level of platelets should be considered.

참고문헌 (10)

  1. Oh Young Bang, "Cancer-Related Stroke: An Emerging Subtype of Ischemic Stroke with Unique Pathomechanisms", 대한뇌졸중영문학회지, 22(1), pp.1~10 (2020), 대한뇌졸중학회[DOI]
  2. 이동건, "종양의 직접 색전에 의한 급성 대뇌동맥 폐색", 대한신경과학회지, 39(1), pp.30~33 (2021), 대한신경과학회[DOI]
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  7. Samuelson Bannow BT, "Management of cancer-associated thrombosis in patients with thrombocytopenia: guidance from the SSC of the ISTH", J Thromb Haemost, 16, pp.1246~1249 (2018)
  8. Iliescu CA, "SCAI expert consensus statement: evaluation, management, and special considerations of cardio-oncology patients in the cardiac catheterization laboratory (endorsed by the Cardiological Society of India, and sociedad Latino Americana de Cardiologıa intervencionista)", Catheter Cardiovasc Interv, 87, pp.E202~E223 (2016)
  9. Park H, "Histological features of intracranial thrombi in stroke patients with cancer", Ann Neurol, 86, pp.143~149 (2019)
  10. Navi BB, "Enoxaparin vs aspirin in patients with cancer and ischemic stroke:The TEACH pilot randomized clinical trial", JAMA Neurol, 75, pp.379~381 (2018)

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