Efficacy of Punch Reduction Prior to Cryotherapy in Patients with Viral Warts: A Case-Control Study in a Single Tertiary Center
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Background: Cutaneous warts are a common complaint to visit dermatologic clinic and its course is variable, ranging from spontaneous resolution to a chronic condition refractory to treatment. Objective: To evaluate the efficacy and safety of punch biopsy for cutaneous warts. Methods: Thirty-nine patients who received punch biopsy for warts were reviewed through charts and photos. Among them, 15 were matched with cryotherapy-only controls in terms of size and location of the wart. We compared the number and cost of treatments between the two groups. Results: Eleven of the total 39 patients were treated with cryotherapy in addition to punch biopsy and the average number of treatments was 4.1±3.3 (mean±standard deviation). In a case-control study, the ratio value of cost was 2.9±3.6 in the experimental group and was 5.9±4.1 in controls (p＜0.05). Conclusion: Punch biopsies can decrease the number and cost of treatment by reducing the size of warts and inducing local inflammation to accelerate resolution. Therefore, punch reduction should be considered as a viable measure to treat warts.
Abstract
Background: Cutaneous warts are a common complaint to visit dermatologic clinic and its course is variable, ranging from spontaneous resolution to a chronic condition refractory to treatment. Objective: To evaluate the efficacy and safety of punch biopsy for cutaneous warts. Methods: Thirty-nine patients who received punch biopsy for warts were reviewed through charts and photos. Among them, 15 were matched with cryotherapy-only controls in terms of size and location of the wart. We compared the number and cost of treatments between the two groups. Results: Eleven of the total 39 patients were treated with cryotherapy in addition to punch biopsy and the average number of treatments was 4.1±3.3 (mean±standard deviation). In a case-control study, the ratio value of cost was 2.9±3.6 in the experimental group and was 5.9±4.1 in controls (p＜0.05). Conclusion: Punch biopsies can decrease the number and cost of treatment by reducing the size of warts and inducing local inflammation to accelerate resolution. Therefore, punch reduction should be considered as a viable measure to treat warts.
참고문헌 (16)
- Goldsmith LA, "Fitzpatrick's dermatology in general medicine", pp.2421~2433 (2012), McGraw-Hill Medical
- Benton EC, "Therapy of cutaneous warts", Clin Dermatol, 15, pp.449~455 (1997)
- Kilkenny M, "The prevalence of common skin conditions in Australian school students: 1. Common, plane and plantar viral warts", Br J Dermatol, 138, pp.840~845 (1998)
- Kyriakis K, "Lifetime prevalence fluctuations of common and plane viral warts", J Eur Acad Dermatol Venereol, 21, pp.260~262 (2007)
- van Haalen FM, "Warts in primary schoolchildren: prevalence and relation with environmental factors", Br J Dermatol, 161, pp.148~152 (2009)
- Massing AM, "Natural history of warts. A two-year study", Arch Dermatol, 87, pp.306~310 (1963)
- Sterling JC, "Guidelines for the management of cutaneous warts", Br J Dermatol, 144, pp.4~11 (2001)
- Gibbs S, "Local treatments for cutaneous warts: systematic review", BMJ, 325, pp.461~ (2002)
- Bacelieri R, "Cutaneous warts: an evidencebased approach to therapy", Am Fam Physician, 72, pp.647~652 (2005)
- Bruggink SC, "HPV type in plantar warts influences natural course and treatment response: secondary analysis of a randomised controlled trial", J Clin Virol, 57, pp.227~232 (2013)
- Micali G, "Management of cutaneous warts: an evidence-based approach", Am J Clin Dermatol, 5, pp.311~317 (2004)
- Dall'oglio F, "Treatment of cutaneous warts: an evidence-based review", Am J Clin Dermatol, 13, pp.73~96 (2012)
- Kwok CS, "Topical treatments for cutaneous warts", Cochrane Database Syst Rev, (9), pp.CD001781~ (2012)
- Sterling JC, "British Association of Dermatologists'guidelines for the management of cutaneous warts 2014", Br J Dermatol, 171, pp.696~712 (2014)
- Seon-Pil Jin, "A Rapidly Regressing Wart Following Biopsy", Annals of Dermatology, 23(1), pp.123~124 (2011), 대한피부과학회
- Coleman N, "Immunological events in regressing genital warts", Am J Clin Pathol, 102, pp.768~774 (1994)