본문 바로가기
KERD
논문KCI 등재

노인에서 연령에 따른 혈압과 인지기능의 관계

Relationship between Blood Pressure and Cognitivi Function according to Age in Elderly Adults

신민호|조기현|권순석|남해성|손의주|김재민|손명호|정슬기
대한신경과학회 (Korean Neurological Association)|2004.02|대한신경과학회지 (Journal of the Korean Neurological Association)|제22권 제1호|pp. 16-21

0

조회

0

다운로드

1

인용

0

참고문헌

주제분류신경과학

초록

Abstract

It has been reported that the association between blood pressure and cognitive impairment could be modified by factors such as gender, education, and Apo E genotypes. This study was aimed to investigate whether 'age' could also be a modifier of the association. Methods: The study group consisted of 489 participants aged 65 years or over who lived in Namwon, Korea. The presence of hypertension was ascertained by the measurement of their resting blood pressure. A cognitive impairment was considered to be present when a Korean Mini-Mental State Examination score was less than 19 (30th percentile). Results: A higher systolic blood pressure was significantly associated with cognitive impairment, after an adjustment for age, gender, education, and occupation. However, the significance was lost in subjects aged 71 or over. Conclusions: High systolic blood pressure is a factor strongly associated with cognitive impairment in an aged population. However, in the subjects with far advanced age, the association is not significant. Further studies are required to elucidate whether blood pressure lowering strategies should be differentiated according to age in order to reduce cognitive impairment.

참고문헌 (32)

  1. "Incidence and outcome of mild cognitive impairment in a population-based prospective cohort", 59, pp.1594~1599 (2002)
  2. "To what degree does cognitive impairment in Alzheimer's disease predict dependence of patients on caregivers?", 2, pp.6~ (2002)
  3. "Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset", 88, pp.1337~1342 (1998)
  4. "Risk factors for Alzheimer's disease: a prospective analysis from the Canadian Study of Health and Aging", 156, pp.445~453 (2002)
  5. "Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam study", 349, pp.151~154 (1997)
  6. "Vascular dementia. Incidence and risk factors in the Canadian Study of Health and Aging", 31, pp.1487~1493 (2000)
  7. "Midlife blood pressure and neuritic plaques, neurofibrillary tangles, and brain weight at death; the HAAS", 21, pp.57~62 (2000)
  8. "Vascular risk and cognitive impairment in an older, British, African- Caribbean population", 49, pp.263~269 (2001)
  9. "Long-term predictors of cognitive outcome in a cohort of older people with hypertension", 177, pp.66~71 (2000)
  10. "Antihypertensive drugs and incidence of dementia: the Rotterdam Study", 22, pp.407~412 (2001)
  11. "Hypertension and related factors in the etiology of Alzheimer's disease", 977, pp.29~36 (2002)
  12. "Cognitive impairment without dementia in older people: prevalence, vascular risk factors, impact on disability. The Italian Longitudinal Study on Aging", pp.775~782 (2000)
  13. "Blood pressure and performance on the Mini-Mental State Examination in the very old. Cross-sectional and longitudinal data from the Kungsholmen project", 145, pp.1106~1113 (1997)
  14. "The incidence of dementia:a meta- analysis", 51, pp.728~733 (1998)
  15. "Diagnostic and Statistical Manual of Mental Disorder", 4th ed (1994), Washington DC
  16. "Measures and meaning of blood pressure", 355, pp.159~ (2000)
  17. "A validity study on the Korean Mini-Mental State Examination (K-MMSE) in dementia patients", 15, pp.300~308 (1997)
  18. "Mini-Mental State. A practical method for grading the cognitive state of patients for the clinician", 12, pp.189~198 (1975)
  19. "The Mini-Mental State Examination:A comprehensive review", 40, pp.922~935 (1992)
  20. "The meaning of cognitive impairment in the elderly", 33, pp.228~235 (1985)
  21. "The Mini-Mental State Examination in a cohort of illiterate elderly patients", 44, pp.495(Abstr)~ (1998)
  22. "Population- based norms for the Mini-Mental State Examination by age and educational level", 269, pp.2386~2391 (1993)
  23. "The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC Ⅵ)", 157, pp.2143~2146 (1997)
  24. "The association between midlife blood pressure levels and late-life cognitive function. The Honolulu-Asia Aging Study", 274, pp.1846~1851 (1995)
  25. "Critically attained threshold of cerebral hypoperfusion:the CATCH hypothesis of Alzheimer's pathogenesis", 21, pp.331~342 (2000)
  26. "The role of cerebra ischemia in Alzheimer's disease", 21, pp.321~330 (2000)
  27. "Incidence and risk factors of silent brain infarcts in the population-based Rotterdam Scan Study", 34, pp.392~396 (2003)
  28. "Association between blood pressure levels over time and brain atrophy in the elderly", 24, pp.304~313 (2003)
  29. "Variability in midlife systolic blood pressure is related to late-life brain white matter lesions. The Honolulu-Asia Aging study", 33, pp.26~30 (2002)
  30. "Analysis of causative factors and effects to cognitive functions of cerebral white matter changes", 19, pp.471~477 (2002)
  31. "Hemodynamics of deformed microvessels in Alzheimer's disease brain", 826, pp.75~91 (1997)
  32. "A study on the prevalence of dementia and its related factors in the rural elderly", 12, pp.628~646 (1994)

관련 논문AI추천

Low Diastolic Blood Pressure and Cognitive Decline in Korean Elderly People: The Korean Longitudinal Study on Cognitive Aging and Dementia김태희, Bong-Jo Kim, Dong Woo Lee, Dong Young Lee, Dongyun Lee, Hyeon Jeong, Hyun-Ghang Jeong, Jae Young Park, Jeong Lan Kim, Jin Hyeong Jhoo, Ji Won Han, Ji-Young Seo, Jong Bin Bae, Jong Chul Youn, Jong Woo Hong, Joon Hyuk Park, Jung Jae Lee, Ju Ri Lee, Kayoung Kim, Ki Woong Kim, Kyoung Hwan Lee, Kyuhee Han, Kyung Phil Kwak, Seok Bum Lee, Seok Woo Moon, Seonjeong Byun, Seung-Ho Ryu, Seung Wan Suh, Shin Gyeom Kim, Taehyun Kim, Yoonseop So대한신경정신의학회 · PSYCHIATRY INVESTIGATION2020 · 제17권 제1호당뇨병을 가진 노인에서의 혈압과 인지기능 사이의 관련성김봉조, 박철수, 서지영, 이동윤, 이소영, 이소진, 이철순, 제남주, 차보석대한생물치료정신의학회 · 생물치료정신의학2015 · 제21권 제2호노인에서 외상 후 스트레스 장애의 증상과 혈압의 연관성강석훈, 고창민, 김태용, 방유진, 소형석, 정혜경, 최진희대한불안의학회 · 대한불안의학회지2013 · 제9권 제2호치매 및 비치매 노인에서 일상생활수행의 상관 인자김성완, 김재민, 박기형, 신일선, 양수진, 윤진상, 정슬기대한신경과학회 · 대한신경과학회지2005 · 제23권 제2호추적관찰을 통한 일개 농촌 노인의 인지기능변화와 관련요인강복수, 김상규, 사공준, 이경수, 황태윤대한예방의학회 · 예방의학회지2007 · 제40권 제2호K-MMSE(Korean-Mini Mental State Examination)의 노인 규준 연구강연욱한국심리학회 · 한국심리학회지:일반2006 · 제25권 제2호

이 간행물의 다른 논문 (9건)

한국의 유전성 대사장애 질환이홍진pp. 1-10항혈소판제제에 따른 뇌경색 환잔의 혈소판 응집력의 차이신현철, 차재관, 천상명, 윤고운, 박경원, 김재우, 김상호pp. 11-15알쯔하이머병의 진행 정동에 따른 행동심리적 증상의 변화김태유, 김상윤, 김재우, 박경원, 유봉구, 이상찬pp. 34-39아밀로이드베타단백(Aβ1-42) 투여 후 신경아세포의 보체 C3a수용체와 C5a수용체의 발현최영숙, 감상호, 이광수pp. 52-58거대세포 동맥염과 연관된 뇌경색 1예정두신, 안무영, 양광익, 안병준, 박형국pp. 59-62
원문 보기