3차원 보행분석시스템을 이용한 파킨슨병 환자의 보행 분석
Analysis of Dynamics of Gait in Parkinson's Disease with 3-Demensional Gait Analysis System
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Abstract
Background: Gait disturbance is one of the most disabling symptoms of Parkinson's disease (PD). To better understand of the dynamics of gait in PD, we quantitatively evaluated the spatiotemporal and kinematic parameters of gait in PD patients and normal controls with 3-demensional gait analysis system. Methods: The diagnosis of PD was based on UK Brain Bank criteria. Subjects with PD were recruited from Parkinson disease clinic of Korea University Medical Center. The severity was indicated by Hoehn & Yahr stage and Unified Parkinson disease rating scale (UPDRS). The gait analysis and assessment was performed in the off condition. Results: Thirty PD patients and thirty normal controls were included. The statistical significant results of gait analysis between PD and control groups were as followings; reduced walking velocity, reduced stride length, increased double supporting time, reduced pelvic oblique movement with preserved pelvic tilting, reduced maximal flexion and extension of hip joint, reduced flexion angle of knee joint especially in terminal stance phase and swing phase, and reduced plantar flexion of ankle. But there were no significant difference between PD and control groups in cadence. And these parameters except cadence had significant correlation with clinical disability in PD patients. The cadence did not correlated significantly with clinical disability. Conclusions: The PD patients showed statistically gait cycle change with preserved cadence, reduced range of motion in hip, knee, and ankle joint with preserved ankle dorsiflexion in the profiles. These features were aggravated in advanced stage.
참고문헌 (29)
- Victor M, "Adams and Victor's Principles of Neurology", pp.1128~1137 (2001), McGraw Hill
- Morris M, "Abnormalities in the stride length -cadence relation in parkinsonian gait", pp.61~69 (1998)
- Blin O, "Quantitative analysis of gait in Parkinson patients:increased variability of stride length", 98, pp.91~97 (1990)
- Pedersen SW, "Gait analysis,isokinetic muscle strength measurement in patients with Parkinson's disease", 29, pp.67~74 (1997)
- O'Sullivan JD, "Gait analysis in patients with Parkinson's disease and motor fluctuations:influence of levodopa and comparison with other measures of motor function", 13, pp.900~906 (1998)
- Ebersbach G, "Interference of rhythmic constraint on gait in healthy subjects and patients with early Parkinson's disease:evidence for impaired locomotor pattern generation in early Parkinson's disease", 14, pp.619~625 (1999)
- Grasso R, "Basal ganglia and gait control:apomorphine administration and internal pallidum stimulation in Parkinson's disease", 126, pp.139~148 (1999)
- Ferrarin M, "Quantitative analysis of gait in Parkinson's disease:a pilot study on the effects of bilateral sub-thalamic stimulation", 16, pp.135~148 (2002)
- Siegel KL, "Effects of bilateral posteroventral pallidotomy on gait of subjects with Parkinson disease", 57, pp.198~204 (2000)
- Elton RL, "Member of the UPDRS Development Committee Recent development in Parkinson's disease", pp.153~164 (1987), Macmillan
- Gibb WR, "The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease", 51, pp.745~752 (1988)
- Murray MP, "Walking patterns of men with Parkinsonism", 57, pp.278~294 (1978)
- Morris ME, "Temporal stability of gait in Parkinson's disease", 76, pp.763~789 (1996)
- Kerrigan DC, "Biomechanical gait alterations independent of sped in the healthy elderly:evidence for specific limiting impairments", 79, pp.317~322 (1998)
- Ostrosky KM, "A comparison of gait characteristics in young and old subjects", 74, pp.637~646 (1994)
- Thaut MH, "Rhythmic auditory stimulation in gait training for Parkinson's disease patients", 11, pp.193~200 (1996)
- Morris ME, "Constraints on the kinetic,kinematic and spatiotemporal parameters of gait in Parkinson's disease", 18, pp.461~483 (1999)
- Shan DE, "Gait analysis in advanced Parkinson's disease--effect of levodopa and tolcapone", 28, pp.70~75 (2001)
- Lewis GN, "Stride length regulation in Parkinson's disease:the use of extrinsic visual cues", 123, pp.2077~2090 (2000)
- Morris ME, "The biomechanics and motor control of gait in Parkinson disease", pp.459~470 (2001)
- Dietz V, "Locomotor capacity of spinal cord in paraplegic patients", 37, pp.574~582 (1995)
- tetrapods, "Control of locomotion in bipeds", 2, pp.59~62 (1997), Williams and Wilkins
- Rossignol S, "Locomotor capacities after complete and partial lesions of the spinal cord", 56, pp.449~463 (1996)
- Eidelberg E, "Locomotor control in macaque monkeys", 104, pp.647~663 (1981)
- Marsden CD, "in patients with Parkinson's disease on chronic levodopa therapy", pp.292~296
- Marsden CD, "Slowness of movement in Parkinson's disease", 4 suppl 1, pp.26~37 (1989)
- Steiger MJ, "Disordered axial movement in Parkinson's disease", 61, pp.645~648 (1996)
- Benecke R, "Disturbance of sequential movements in patients with Parkinson's disease", 110, pp.361~379 (1987)
- Berardelli A, "Scaling of the size of the first agonist EMG burst during rapid wrist movements in patients with Parkinson's disease", 49, pp.1273~1279 (1986)