Analysis of Microscopic Examination of Pulled Out Hair in Telogen Effluvium Patients
0
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Background: Telogen effluvium (TE) is characterized by massive hair shedding and results from an abrupt conversion of anagen to telogen. Differentiation of TE with other hair disorders showing massive hair shedding is difficult. Objective: To evaluate the morphologic characteristics of pulled out hair of TE. Methods: We analyzed microscopic examination of pulled out hairs by hair pull test in TE patients, and compared these hairs with pulled out hairs in diffuse alopecia areata (AA) patients and healthy volunteers. Results: Hair microscopic examination in 44 TE patients (370 hairs) and 30 healthy volunteers (295 hairs) were as follows: typical club hair, 32.7%, 62.7%; club hair with tail, 23.5%, 23.7%; club hair with remnant sheath, 23.0%, 6.8%; club hair with both tail and remnant sheath, 18.9%, 5.4%; and unclassified hair, 1.9%, 1.4%. The examination in 7 diffuse AA patients (63 hairs) was as follows: typical club hair, 23.9%; atypical club hair, 47.7%; and distinctive AA hair, 28.4%. There was statistical difference between TE patients and healthy volunteers group (p=0.000). Conclusion: Increased atypical club hair in microscopic hair examination might be characteristics of TE.
Abstract
Background: Telogen effluvium (TE) is characterized by massive hair shedding and results from an abrupt conversion of anagen to telogen. Differentiation of TE with other hair disorders showing massive hair shedding is difficult. Objective: To evaluate the morphologic characteristics of pulled out hair of TE. Methods: We analyzed microscopic examination of pulled out hairs by hair pull test in TE patients, and compared these hairs with pulled out hairs in diffuse alopecia areata (AA) patients and healthy volunteers. Results: Hair microscopic examination in 44 TE patients (370 hairs) and 30 healthy volunteers (295 hairs) were as follows: typical club hair, 32.7%, 62.7%; club hair with tail, 23.5%, 23.7%; club hair with remnant sheath, 23.0%, 6.8%; club hair with both tail and remnant sheath, 18.9%, 5.4%; and unclassified hair, 1.9%, 1.4%. The examination in 7 diffuse AA patients (63 hairs) was as follows: typical club hair, 23.9%; atypical club hair, 47.7%; and distinctive AA hair, 28.4%. There was statistical difference between TE patients and healthy volunteers group (p=0.000). Conclusion: Increased atypical club hair in microscopic hair examination might be characteristics of TE.
참고문헌 (15)
- Grover C, "Telogen effluvium", Indian J Dermatol Venereol Leprol, 79, pp.591~603 (2013)
- Shapiro J, "Clinical practice. Hair loss in women", N Engl J Med, 357, pp.1620~1630 (2007)
- Mubki T, "Evaluation and diagnosis of the hair loss patient: part I. History and clinical examination", J Am Acad Dermatol, 71, pp.415.e1~415.e15 (2014)
- McDonald KA, "Hair pull test : evidence-based update and revision of guidelines", J Am Acad Dermatol, 76, pp.472~477 (2017)
- Hillmann K, "Diagnosis of hair disorders", Semin Cutan Med Surg, 28, pp.33~38 (2009)
- Shapiro J, "Practical management of hair loss", Can Fam Physician, 46, pp.1469~1477 (2000)
- McElwee KJ, "Hair physiology and its disorders", Drug Discov Today Dis Mech, 5, pp.e163~e171 (2008)
- Hardy MH, "The secret life of the hair follicle", Trends Genet, 8, pp.55~61 (1992)
- Jackson AJ, "How to diagnose hair loss", Dermatol Clin, 31, pp.21~28 (2013)
- Alkhalifah A, "Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis", J Am Acad Dermatol, 62, pp.177~188 (2010)
- Otberg N, "Primary cicatricial alopecias", Dermatol Clin, 31, pp.155~166 (2013)
- Van Neste D, "Exogen hair characterization in human scalp", Skin Res Technol, 13, pp.436~443 (2007)
- Hoffmann R, "TrichoScan : combining epiluminescence microscopy with digital image analysis for the measurement of hair growth in vivo", Eur J Dermatol, 11, pp.362~368 (2001)
- Piérard GE, "EEMCO guidance for the assessment of hair shedding and alopecia", Skin Pharmacol Physiol, 17, pp.98~110 (2004)
- Van Neste MD, "Assessment of hair loss : clinical relevance of hair growth evaluation methods", Clin Exp Dermatol, 27, pp.358~365 (2002)