Relationship of Hair Regrowth Pattern in Alopecia Areata Patches According to DIMT Classification with Treatment Modalities and Patch Size: A Retrospective Cross-Sectional Analysis
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Background: The morphology of hair regrowth in alopecia areata (AA) patches could be classified into four types, namely diffuse, irregular, marginal, and targetoid patterns, ac- cording to the DIMT classification. However, factors affecting hair regrowth patterns have not been investigated. Objective: We investigated whether the DIMT-classified hair regrowth patterns of AA patches are associated with treatment modality and patch size. Methods: We conducted a retrospective, cross-sectional study of 152 AA patches with hair regrowth. Results: The associations between the diffuse pattern and patch size >2 cm ( =0.006; odds ratio [OR]: 0.36, 95% confidence interval [CI]: 0.17~0.74), between the irregular pat- tern and triamcinolone acetonide intralesional injection ( <0.001; OR: 274.87, 95% CI: 25.75~2,933.56), between the marginal pattern and systemic and topical corticosteroid ( =0.018; OR: 4.89, 95% CI: 1.31~18.27), and between the targetoid pattern and patch size >2 cm ( =0.028; OR: 2.50, 95% CI: 1.10~5.68) were statistically significant. Conclusion: Treatment modalities and patch size are the factors affecting hair regrowth patterns in AA patches.
Abstract
Background: The morphology of hair regrowth in alopecia areata (AA) patches could be classified into four types, namely diffuse, irregular, marginal, and targetoid patterns, ac- cording to the DIMT classification. However, factors affecting hair regrowth patterns have not been investigated. Objective: We investigated whether the DIMT-classified hair regrowth patterns of AA patches are associated with treatment modality and patch size. Methods: We conducted a retrospective, cross-sectional study of 152 AA patches with hair regrowth. Results: The associations between the diffuse pattern and patch size >2 cm ( =0.006; odds ratio [OR]: 0.36, 95% confidence interval [CI]: 0.17~0.74), between the irregular pat- tern and triamcinolone acetonide intralesional injection ( <0.001; OR: 274.87, 95% CI: 25.75~2,933.56), between the marginal pattern and systemic and topical corticosteroid ( =0.018; OR: 4.89, 95% CI: 1.31~18.27), and between the targetoid pattern and patch size >2 cm ( =0.028; OR: 2.50, 95% CI: 1.10~5.68) were statistically significant. Conclusion: Treatment modalities and patch size are the factors affecting hair regrowth patterns in AA patches.
참고문헌 (9)
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