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과관류증후군으로 유발된 난치성부분뇌전증지속상태 치료 중 발생한 치명적 프로포폴주입증후군

Fatal Propofol Infusion Syndrome Associated with Refractory Partial Status Epilepticus in a Patient with Cerebral Hyperperfusion Syndrome

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초록

Status epilepticus is rare complication of cerebral hyperperfusion syndrome and is a critical medical emergency thatrequires potent anesthetics. Propofol has the advantages of being rapid-acting and possessing a weakercardiopulmonary suppression profile, but its use is associated with serious propofol infusion syndrome. We reportherein a case of cerebral hyperperfusion syndrome after carotid endarterectomy presenting with refractory partial statusepilepticus and fatal outcome associated with propofol infusion syndrome.

Abstract

Status epilepticus is rare complication of cerebral hyperperfusion syndrome and is a critical medical emergency thatrequires potent anesthetics. Propofol has the advantages of being rapid-acting and possessing a weakercardiopulmonary suppression profile, but its use is associated with serious propofol infusion syndrome. We reportherein a case of cerebral hyperperfusion syndrome after carotid endarterectomy presenting with refractory partial statusepilepticus and fatal outcome associated with propofol infusion syndrome.

참고문헌 (10)

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  2. Sato K, "A case of hyperperfusion syndrome treated successfully by propofol", Masui, 50, pp.25~28 (2001)
  3. Morioka T, "Electroencephalographic evaluation of cerebral hyper-perfusion syndrome following superficial temporal artery-middle cer-ebral artery anastomosis", Neurol Med Chirur, 53, pp.388~395 (2013)
  4. Hamamura T, "Cerebral hyperperfusion syndrome associated with non-con-vulsive status epilepticus following superficial temporal artery-middle cerebral artery anastomosis. Case report", Neurol Med Chirur (Tokyo), 50, pp.1099~1104 (2010)
  5. Reigel MM, "Cerebral hyperperfusion syndrome: a cause of neurologic dysfunction after carotid endarterectomy", J Vas Surg, 5, pp.628~634 (1987)
  6. Kam PC, "Propofol infusion syndrome", Anesthesia, 62, pp.690~701 (2007)
  7. Fodale V, "Propofol infusion syndrome: an overview of a perplexing disease", Drug Saf, 31, pp.293~303 (2008)
  8. Haase R, "Lactic acidosis following short-term pro-pofol infusion may be an early warning of propofol infusion syndrome", J Neurosurg Anesthesiol, 17, pp.122~123 (2005)
  9. Eriksen J, "A case of suspected non-neurosurgical adult fatal propofol infusion syndrome", Acta anaesthesiol Scand, 50, pp.117~119 (2006)
  10. Merz TM, "Propofol infusion syn-drome-a fatal case at a low infusion rate", Anesth Analge, 103, pp.1050~ (2006)

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