Extranodal NK/T-Cell Lymphoma, Nasal Type, Extranasal and Ulcerative Blister Variant, Case Report
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
The extranodal natural killer (NK) T-cell lymphoma of nasal type is a form of lymphoma that falls within the WHO/EORTC 2018 classification of cutaneous T-cell lymphomas. It is characterized for being aggressive, infrequent, and destroying midline facial structures; however, it can also be in primary or secondary form at extranasal sites, such as the skin or the gastrointestinal tract, among others. We report the case of an 18-year-old patient with an extranodal NK/T-cell lymphoma located in an extranasal site. The clinical presenta- tion is characterized for being multifocal and with erythematous-violaceous plaques that progress to hemorrhagic blisters and necrotic ulcers. Although this type of lymphoma has been reported previously by others, the presence of blisters is an atypical finding, which we believe has been described only in one case in the medical literature.
Abstract
The extranodal natural killer (NK) T-cell lymphoma of nasal type is a form of lymphoma that falls within the WHO/EORTC 2018 classification of cutaneous T-cell lymphomas. It is characterized for being aggressive, infrequent, and destroying midline facial structures; however, it can also be in primary or secondary form at extranasal sites, such as the skin or the gastrointestinal tract, among others. We report the case of an 18-year-old patient with an extranodal NK/T-cell lymphoma located in an extranasal site. The clinical presenta- tion is characterized for being multifocal and with erythematous-violaceous plaques that progress to hemorrhagic blisters and necrotic ulcers. Although this type of lymphoma has been reported previously by others, the presence of blisters is an atypical finding, which we believe has been described only in one case in the medical literature.
참고문헌 (20)
- Akbar M, "Extranodal NK", T-cell lymphoma, nasal type, with extranasal presentation-a case report and a review of the literature, 2020, pp.59, 1480~1487
- Willemze R, "The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas", Blood, 133, pp.1703~1714 (2019)
- Barrionuevo C, "Extranodal NK", T-cell lymphoma, nasal type : study of clinicopathologic and prognosis factors in a series of 78 cases from Peru, 2007, pp.15, 38~44
- Harabuchi Y, "Extranodal natural killer", T-cell lymphoma, nasal type : basic science and clinical progress, 2019, pp.7, 141~
- Liu QF, "Immunophenotypic and clinical differences between the nasal and extranasal subtypes of upper aerodigestive tract natural killer", T-cell lymphoma, 2014, pp.88, 806~813
- Lee WJ, "Cutaneous extranodal natural killer", T-cell lymphoma : a comparative clinicohistopathologic and survival outcome analysis of 45cases according to the primary tumor site, 2014, pp.70, 1002~1009
- 정성훈, "Frontline therapy for newly diagnosed patients with multiple myeloma", Blood Research, 55, pp.37~42 (2020), 대한혈액학회[DOI]
- Schimmel J, "A case of primary cutaneous extranodal NK", T-cell lymphoma in an African male, 2019, pp.58, e172~e173
- Diallo M, "Primary cutaneous extranodal NK", T-cell lymphoma mimicking a large B-cell lymphoma(leg type), 2017, pp.2, 3~
- Maeda K, "Association of vesiculobullous eruptions with mycosis fungoides", Dermatologica, 174, pp.34~38 (1987)
- Medina-Ortega AP, "Relationship between Epstein-Barr virus and cancer development", Iatreia, 30, pp.131~145 (2017)
- Choi YL, "Extranodal NK", T-cell lymphoma with cutaneous involvement : ‘nasal’vs. ‘nasal-type’ subgroups--a retrospective study of 18 patients, 2009, pp.160, 333~337
- Rozas-Muñoz E, "Extranodal natural killer", T-cell lymphoma, nasal type : a Spanish multicentric retrospective survey, 2018, pp.28, 64~70
- Gualco G, "Clinicopathologic and molecular features of 122 Brazilian cases of nodal and extranodal NK", T-cell lymphoma, nasal type, with EBV subtyping analysis, 2011, pp.35, 1195~1203
- Suzuki R, "Prognostic factors for mature natural killer (NK) cell neoplasms: aggressive NK cell leukemia and extranodal NK cell lymphoma, nasal type", Ann Oncol, 21, pp.1032~1040 (2010)
- Wu X, "A clinical study of 115 patients with extranodal natural killer", T-cell lymphoma, nasal type, 2008, pp.20, 619~625
- Stoughton RB, "Mechanisms of blister formation", AMA Arch Derm, 76, pp.584~590 (1957)
- Tse E, "The diagnosis and management of NK", T-cell lymphomas, 2017, pp.10, 85~
- Lee J, "Extranodal natural killer T-cell lymphoma, nasal-type : a prognostic model from a retrospective multicenter study", J Clin Oncol, 24, pp.612~618 (2006)
- Kim TM, "Clinical heterogeneity of extranodal NK", T-cell lymphoma, nasal type: a national survey of the Korean Cancer Study Group, 2008, pp.19, 1477~1484