다초점운동신경병 증례: 초음파의 보완적인 역할
Multifocal Motor Neuropathy: Complementary Role of Ultrasound Hae Joo
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Multifocal motor neuropathy (MMN) is an uncommon, asymmetric motor neuropathy. As MMN is a treatable disorder, its differentiation from lower motor neuron disease is important. Evidence of conduction block (CB) or positive IgM anti-GM1 is considered one of important markers for the diagnosis. However, some patients with atypical MMN have no detectable CB or anti-GM1 antibody. We experienced a case of MMN with focal nerve enlargement on ultrasound. Ultrasound can be a valuable tool in supporting the diagnosis of MMN.
Abstract
Multifocal motor neuropathy (MMN) is an uncommon, asymmetric motor neuropathy. As MMN is a treatable disorder, its differentiation from lower motor neuron disease is important. Evidence of conduction block (CB) or positive IgM anti-GM1 is considered one of important markers for the diagnosis. However, some patients with atypical MMN have no detectable CB or anti-GM1 antibody. We experienced a case of MMN with focal nerve enlargement on ultrasound. Ultrasound can be a valuable tool in supporting the diagnosis of MMN.
참고문헌 (10)
- Van Asseldonk JT, "Multifocal motor neuropathy", Lancet Neurol, 4, pp.309~319 (2005)[DOI]
- Olney RK, "Consensus criteria for the diagnosis of multifocal motor neuropathy", Muscle Nerve, 27, pp.117~121 (2003)[DOI]
- 석정임, "말초신경초음파검사를 이용한 흔한 신경포착부위 검사; 단면적기준치와 정상변이", 대한신경과학회지, 33(1), pp.8~12 (2015), 대한신경과학회
- Pestronk A, "A treatable multifocal motor neuropathy with antibodies to GM1 ganglioside", Ann Neurol, 24, pp.73~78 (1988)[DOI]
- Pakiam AS, "Multifocal motor neuropathy without overt conduction block", Muscle Nerve, 21, pp.243~245 (1998)[DOI]
- Beekman R, "Ultrasonography shows extensive nerve enlargements in multifocal motor neuropathy", Neurology, 65, pp.305~307 (2005)[DOI]
- Grimm A, "Nerve ultrasound for differentiation between amyotrophic lateral sclerosis and multifocal motor neuropathy", J Neurol, 262, pp.870~880 (2015)[DOI]
- Loewenbruck KF, "Nerve ultrasound in the differentiation of multifocal motor neuropathy (MMN) and amyotrophic lateral sclerosis with predominant lower motor neuron disease (ALS", LMND), 2016, pp.263, 35~44
- Granata G, "Ultrasound visualization of nerve morphological alteration at the site of conduction block", Muscle Nerve, 40, pp.1068~1070 (2009)[DOI]
- Kerasnoudis A, "Multifocal motor neuropathy: correlation of nerve ultrasound, electrophysiological, and clinical findings", J Peripher Nerv Syst, 19, pp.165~174 (2014)[DOI]