급성허혈뇌졸중의 혈관내재개통치료에 대한 최신 지견
An Update of Recent Guideline for the Endovascular Recanalization Therapy in Acute Ischemic Stroke
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초록
Endovascular recanalization therapy (ERT) has been proven its efficacy in improving prognosis of acute ischemic stroke with intracranial large artery occlusion. Before the DAWN and DEFUSE 3 trials, ERT was recommended for stroke patients who could be treated within 6 hours after the onset of symptoms and the prognosis after ERT has been known time-dependent. However, the most recently published 2 ERT trials performed more than time window of 6 hours showed significant efficacy of ERT to compare with conservative therapy in selected patients. Now we should apply the result of new trials of ERT in the extended time window clinically. Herein, the result of recent ERT trials and the predictive factors affecting prognosis beyond the concept of time in ERT will be discussed.
Abstract
Endovascular recanalization therapy (ERT) has been proven its efficacy in improving prognosis of acute ischemic stroke with intracranial large artery occlusion. Before the DAWN and DEFUSE 3 trials, ERT was recommended for stroke patients who could be treated within 6 hours after the onset of symptoms and the prognosis after ERT has been known time-dependent. However, the most recently published 2 ERT trials performed more than time window of 6 hours showed significant efficacy of ERT to compare with conservative therapy in selected patients. Now we should apply the result of new trials of ERT in the extended time window clinically. Herein, the result of recent ERT trials and the predictive factors affecting prognosis beyond the concept of time in ERT will be discussed.
참고문헌 (29)
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