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POEMS 증후군 환자의 뇌혈관병증에 의한 뇌졸중

Ischemic Stroke with Cerebral Vasculopathy in POEMS Syndrome

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초록

Ischemic stroke caused by the cerebral vasculopathy is a rare complication of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome. We present a case of recurrent ischemic strokes caused by cerebral vasculopathy in a patient with POEMS syndrome. A 34-year-old man presented with gait disturbance and dizziness. Brain magnetic resonance imaging demonstrated acute ischemic stroke in the middle cerebral artery-anterior cerebral artery (MCA-ACA) border zones of bilateral hemispheres. Repeated angiographic studies showed progressive worsening of the left distal internal carotid artery, ACA, and MCA stenoses, along with sustained steno-occlusion of right MCA

Abstract

Ischemic stroke caused by the cerebral vasculopathy is a rare complication of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome. We present a case of recurrent ischemic strokes caused by cerebral vasculopathy in a patient with POEMS syndrome. A 34-year-old man presented with gait disturbance and dizziness. Brain magnetic resonance imaging demonstrated acute ischemic stroke in the middle cerebral artery-anterior cerebral artery (MCA-ACA) border zones of bilateral hemispheres. Repeated angiographic studies showed progressive worsening of the left distal internal carotid artery, ACA, and MCA stenoses, along with sustained steno-occlusion of right MCA

참고문헌 (10)

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  6. Dupont SA, "Cerebral infarction in POEMS syndrome: incidence, risk factors, and imaging characteristics", Neurology, 73, pp.1308~1312 (2009)
  7. Fu FW, "Ischemic stroke in patients with POEMS syndrome : a case report and comprehensive analysis of literature", Oncotarget, 8, pp.89406~89424 (2017)
  8. Yamaguchi I, "Coexistence of quasi-moyamoya disease and POEMS syndrome in a patient with intracranial hemorrhage : a case report and literature review", NMC Case Rep J, 4, pp.5~9 (2017)
  9. Sommer B, "Therapeutic challenges in a patient with POEMS syndrome and recurrent stroke : presentation of a case and review of the literature", Acta Neurol Belg, 112, pp.9~13 (2012)
  10. Yaghi S, "Paraneoplastic progressive vasculopathy as the presenting manifestation of polyneuropathy, organomegaly, endocrinopathy or edema, M-Spike, and skin manifestations: a case report", J Stroke Cerebrovasc Dis, 25, pp.e103~e107 (2016)

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