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메트로니다졸 독성 뇌병증으로 인한 안구운동발작

Oculogyric Crisis Due to Metronidazole Toxic Encephalopathy

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초록

Oculogyric crisis is an acute dystonia involving ocular muscles characterized by sustained conjugate upward or lateral deviation of the eyes. Metronidazole is a commonly used antimicrobial agent in treatment of anaerobic infections. However, its long-term use can cause toxic encephalopathy particularly in patients with hepatic dysfunction. Here, we describe a case of oculogyric crisis as a presenting manifestation of metronidazole-induced encephalopathy.

Abstract

Oculogyric crisis is an acute dystonia involving ocular muscles characterized by sustained conjugate upward or lateral deviation of the eyes. Metronidazole is a commonly used antimicrobial agent in treatment of anaerobic infections. However, its long-term use can cause toxic encephalopathy particularly in patients with hepatic dysfunction. Here, we describe a case of oculogyric crisis as a presenting manifestation of metronidazole-induced encephalopathy.

참고문헌 (8)

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  6. Roy U, "Clinical and neuroradiological spectrum of metronidazole induced encephalopathy: our experience and the review of literature", J Clin Diagn Res, 10, pp.OE01~OE09 (2016)
  7. Kim E, "MR imaging of metronidazole-induced encephalopathy : lesion distribution and diffusion-weighted imaging findings", AJNR Am J Neuroradiol, 28, pp.1652~1658 (2007)
  8. Neychev VK, "The basal ganglia and cerebellum interact in the expression of dystonic movement", Brain, 131, pp.2499~2509 (2008)

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