Lymphangiectatic Variant of Low Grade Malignant Eccrine Spiradenoma
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Low-grade malignant eccrine spiradenoma (spiradenocarcinoma) is a rare sweat glandtumor, which usually arises from a pre- existing benign eccrine spiradenoma. This paperpresents the case of a 55-year-old male who had a lesion in his right elbow for 10 years. Themicroscopic examination revealed a well-demarcated, multilobulated tumor in the dermisand subcutis, which presented with many blood-filled vessels and extensive hemorrhage. The tumor was composed of hyperchromatic, round to oval cells with nucleolar prominence,mild to moderate atypia, and increased mitotic index. Additionally, lymphangiectaticappearance was observed in areas with prominent stromal lymphedema. P53 and Ki-67 hadhigh positivity. Surgical excision of the lesion was performed with adequate surgical margins,and the dissected lymph nodes in the axilla were tumor-negative. After 15 months offollow-up, there was no recurrence or distant metastasis.
Abstract
Low-grade malignant eccrine spiradenoma (spiradenocarcinoma) is a rare sweat glandtumor, which usually arises from a pre- existing benign eccrine spiradenoma. This paperpresents the case of a 55-year-old male who had a lesion in his right elbow for 10 years. Themicroscopic examination revealed a well-demarcated, multilobulated tumor in the dermisand subcutis, which presented with many blood-filled vessels and extensive hemorrhage. The tumor was composed of hyperchromatic, round to oval cells with nucleolar prominence,mild to moderate atypia, and increased mitotic index. Additionally, lymphangiectaticappearance was observed in areas with prominent stromal lymphedema. P53 and Ki-67 hadhigh positivity. Surgical excision of the lesion was performed with adequate surgical margins,and the dissected lymph nodes in the axilla were tumor-negative. After 15 months offollow-up, there was no recurrence or distant metastasis.
참고문헌 (9)
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