아산화질소 남용 후에 발생한 아급성연합변성 및 운동신경병
Subacute Combined Degeneration with Motor Neuropathy Following Nitrous Oxide Abuse
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초록
The neurotoxicity of nitrous oxide (N2O) is known to be mainly occurred by interference with action of vitamin B12. A 38-year-old male presented with progressive gait instability after recreational inhalational use of N2O for 2 months. Although spine magnetic resonance image showed typical subacute combined degeneration, nerve conduction study showed motor neuropathy that is atypical findings of vitamin B12 deficiency. This case suggests N2O-induced neuropathy can develop separately from a vitamin B12 deficiency.
Abstract
The neurotoxicity of nitrous oxide (N2O) is known to be mainly occurred by interference with action of vitamin B12. A 38-year-old male presented with progressive gait instability after recreational inhalational use of N2O for 2 months. Although spine magnetic resonance image showed typical subacute combined degeneration, nerve conduction study showed motor neuropathy that is atypical findings of vitamin B12 deficiency. This case suggests N2O-induced neuropathy can develop separately from a vitamin B12 deficiency.
참고문헌 (9)
- Savage S, "The neurotoxicity of nitrous oxide: the facts and "putative" mechanisms", Brain Sci, 4, pp.73~90 (2014)
- Lan SY, "Recreational nitrous oxide abuse related subacute combined degeneration of the spinal cord in adolescents - a case series and literature review", Brain Dev, 41, pp.428~435 (2019)
- 박수현, "해피벌룬으로 인해 발생한 척수신경병", 대한신경과학회지, 38(4), pp.327~329 (2020), 대한신경과학회
- Garakani A, "Neurologic, psychiatric, and other medical manifestations of nitrous oxide abuse: a systematic review of the case literature", Am J Addict, 25, pp.358~369 (2016)
- McCombe PA, "The peripheral neuropathy of vitamin B12deficiency", J Neurol Sci, 66, pp.117~126 (1984)
- Franques J, "Characteristics of patients with vitamin B12-responsive neuropathy: a case series with systematic repeated electrophysiological assessment", Neurol Res, 41, pp.569~576 (2019)
- Li HT, "Clinical and electrodiagnostic characteristics of nitrous oxide-induced neuropathy in Taiwan", Clin Neurophysiol, 127, pp.3288~3293 (2016)
- Morris N, "Severe motor neuropathy or neuronopathy due to nitrous oxide toxicity after correction of vitamin B12deficiency", Muscle Nerve, 51, pp.614~616 (2015)
- Maze M, "Recent advances in understanding the actions and toxicity of nitrous oxide", Anaesthesia, 55, pp.311~314 (2000)