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Primary Sjögren’s Syndrome Presenting with Dyskinesia

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초록

Sjögren’s syndrome (SS) is an autoimmune disease in which lymphocytes invade salivary and tear glands, leading to dry mouth and dry eyes. It is also associated with extraglandular manifestations. The most frequently reported neurological extraglandular manifestations are sensory polyneuropathies. Movement disorders have been reported in only 2% of primary SS patients. In this case, we present a case of primary SS initially manifesting as generalized chorea, which was initially misdiagnosed as tardive dyskinesia.

Abstract

Sjögren’s syndrome (SS) is an autoimmune disease in which lymphocytes invade salivary and tear glands, leading to dry mouth and dry eyes. It is also associated with extraglandular manifestations. The most frequently reported neurological extraglandular manifestations are sensory polyneuropathies. Movement disorders have been reported in only 2% of primary SS patients. In this case, we present a case of primary SS initially manifesting as generalized chorea, which was initially misdiagnosed as tardive dyskinesia.

참고문헌 (10)

  1. Alvarado-Franco NL, "Athetoid movements as initial manifestation of primary Sjögren syndrome", Tremor Other Hyperkinet Mov(N Y), 8, pp.573~ (2018)
  2. Lee KA, "New classification criteria for primary Sjögren’s syndrome and salivary gland ultrasonography", Korean J Med, 92, pp.499~505 (2017)
  3. Berkowitz AL, "The neurology of Sjogren’s syndrome and the rheumatology of peripheral neuropathy and myelitis", Pract Neurol, 14, pp.14~22 (2014)
  4. Dai F, "Clinical characteristics of secondary immune thrombocytopenia associated with primary Sjogren’s syndrome", Front Med(Lausanne), 7, pp.138~ (2020)
  5. Fanchke PV, "Primary Sjögren’s syndrome presenting as a generalized Chorea", Parkinsonism Relat Disord, 11, pp.193~194 (2005)
  6. Kim HA, "The primary Sjogren’s syndrome involving central and peripheral nervous system", J Korean Neurol Assoc, 25, pp.108~111 (2007)
  7. Lin WY, "Various movement disorders in a patient with Sjögren syndrome", Mov Disord, 24, pp.786~788 (2009)
  8. Menezes R, "Movement and other neurodegenerative syndromes in patients with systemic rheumatic diseases : a case series of 8 patients and review of the literature", Medicine(Baltimore), 94, pp.e0971~ (2015)
  9. Ararat K, "Case of primary Sjögren’s syndrome preceded by dystonia", BMJ Case Rep, 2018, pp.bcr2017223468~ (2018)
  10. Feinstein E, "Treatment of secondary chorea : a review of the current literature", Tremor Other Hyperkinet Mov(N Y), 10, pp.22~ (2020)

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