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점진적으로 진행하는 보행장애로 내원한 자발두개내압 저하

Spontaneous Intracranial Hypotension Presenting as Progressive Gait Impairment

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초록

Orthostatic headache is a hallmark symptom of spontaneous intracranial hypotension (SIH). However, SIH can manifest without headache, which can lead to a significant delay in treatment initiation. We hereby report a 70-year-old male with progressive gait disturbance and superficial siderosis. Magnetic resonance myelography showed an extensive extradural cerebrospinal fluid collection in the cervicothoracic spine. After a series of targeted epidural blood patch, the patient’s symptoms significantly improved. SIH should be considered as a potential cause of otherwise unexplained superficial siderosis to prompt an early diagnosis and treatment.

Abstract

Orthostatic headache is a hallmark symptom of spontaneous intracranial hypotension (SIH). However, SIH can manifest without headache, which can lead to a significant delay in treatment initiation. We hereby report a 70-year-old male with progressive gait disturbance and superficial siderosis. Magnetic resonance myelography showed an extensive extradural cerebrospinal fluid collection in the cervicothoracic spine. After a series of targeted epidural blood patch, the patient’s symptoms significantly improved. SIH should be considered as a potential cause of otherwise unexplained superficial siderosis to prompt an early diagnosis and treatment.

참고문헌 (9)

  1. Headache Classification Committee of the International Headache Society(HIS), "The international classification of headache disorders, 3rd edition", Cephalalgia, 38, pp.1~211 (2018)
  2. D’Antona L, "Clinical presentation, investigation findings, and treatment outcomes of spontaneous intracranial hypotension syndrome : a systematic review and meta-analysis", JAMA Neurol, 78, pp.329~337 (2021)
  3. Mokri B, "Spontaneous intracranial hypotension", Continuum(Minneap Minn), 21, pp.1086~1108 (2015)
  4. Schievink WI, "Misdiagnosis of spontaneous intracranial hypotension", Arch Neurol, 60, pp.1713~1718 (2003)
  5. Perez-Vega C, "Spontaneous intracranial hypotension : key features for a frequently misdiagnosed disorder", Neurol Sci, 41, pp.2433~2441 (2020)
  6. Bond KM, "Spontaneous intracranial hypotension : atypical radiologic appearances, imaging mimickers, and clinical look-alikes", AJNR Am J Neuroradiol, 41, pp.1339~1347 (2020)
  7. Sasikumar S, "Isolated gait dysfunction due to intracranial hypotension", Neurology, 91, pp.271~273 (2018)
  8. Wilson D, "Infratentorial superficial siderosis : classification, diagnostic criteria, and rational investigation pathway", Ann Neurol, 81, pp.333~343 (2017)
  9. Kumar N, "Superficial siderosis and CSF hypovolemia : the defect(dural)in the link", Neurology, 69, pp.925~926 (2007)

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