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젊은 COVID-19 뇌경색 환자: 혈관염 소견 및 뇌혈관 협착의 변화

Stroke in a Young Age COVID-19 Patient: Vasculitis Feature and Changes in Cerebral Vessel Stenosis

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초록

Recent studies have shown that coronavirus disease-2019 (COVID-19) infection increased risk of stroke. Significant differences have been identified between the general population and COVID-19 stroke patients. There are unusual patterns of stroke occurred in COVID-19 patient are reported. Pathophysiologic theories about the relationship of COVID-19 infection and stroke are being published. Herein we report a rare case of stroke in a young COVID-19 patient, considered to be the result of vasculitis, and vessel changes that might have been caused by vasospasm based on serial brain imaging follow-up data. And we interpret this case based on pathophysiological characteristics of the severe acute respiratory syndrome coronavirus 2.

Abstract

Recent studies have shown that coronavirus disease-2019 (COVID-19) infection increased risk of stroke. Significant differences have been identified between the general population and COVID-19 stroke patients. There are unusual patterns of stroke occurred in COVID-19 patient are reported. Pathophysiologic theories about the relationship of COVID-19 infection and stroke are being published. Herein we report a rare case of stroke in a young COVID-19 patient, considered to be the result of vasculitis, and vessel changes that might have been caused by vasospasm based on serial brain imaging follow-up data. And we interpret this case based on pathophysiological characteristics of the severe acute respiratory syndrome coronavirus 2.

참고문헌 (8)

  1. Shahjouei S, "SARS-CoV-2 and stroke characteristics : a report from the Multinational COVID-19 Stroke Study Group", Stroke, 52, pp.e117~e130 (2021)
  2. Salabei JK, "COVID-19 coagulopathy : current knowledge and guidelines on anticoagulation", Heart Lung, 50, pp.357~360 (2021)
  3. Abassi Z, "ACE2, COVID-19 infection, inflammation, and coagulopathy : missing pieces in the puzzle", Front Physiol, 11, pp.574753~ (2020)
  4. Alkayed NJ, "Role of endothelial cells and platelets in COVID-related cerebrovascular events", Stroke, 53, pp.2389~2392 (2022)
  5. Gorog DA, "Current and novel biomarkers of thrombotic risk in COVID-19 : a consensus statement from the international COVID-19 thrombosis biomarkers colloquium", Nat Rev Cardiol, 19, pp.475~495 (2022)
  6. Keller E, "Large and small cerebral vessel involvement in severe COVID-19 : detailed clinical workup of a case series", Stroke, 51, pp.3719~3722 (2020)
  7. Hanafi R, "COVID-19 neurologic complication with CNS vasculitis-like pattern", AJNR Am J Neuroradiol, 41, pp.1384~1387 (2020)
  8. Taha M, "Antiphospholipid antibodies in COVID-19 : a meta-analysis and systematic review", RMD Open, 7, pp.e001580~ (2021)

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