치매의 조기 진단
Early Diagnosis of Dementia
0
조회
0
다운로드
11
인용
0
참고문헌
키워드
초록
전체 인구에서 노인들이 차지하는 비율, 이 집단에서 치매의 유병률, 치매 환자들의 치료에 소요되는 사회적 부담 등을 고려해보면 치매는 분명히 공중보건상의 문제이다. 최근 20～30년 전부터 급속도로 발전하고 있는 신경과학은 치매의 병태생리는 물론 치료에도 많은 성과를 거두고 있다. 따라서 치매를 조기에 진단해야 할 필요성은 점점 더 증가하고 있다. 그러나 모든 노인들에게 전 인구 선별 검사를 시행할 것인지, 고위험 집단을 대상으로 할 것인지, 아니면 경도인지장애의 가능성이 있는 노인들을 대상으로 할 것인지에 대해서는 논의의 여지가 있다. 치매의 유병률, 선별 검사의 유용성, 치료의 가능성, 적절한 치료적 개입의 시기를 놓침으로서 부담해야 하는 사회적 부담 등을 고려해보면 최소한 고위험 집단이나 경도인지장애의 가능성이 있는 노인들에게는 선별 검사를 권유할 만하다고 생각된다.
Abstract
Considering the proportion of the elderly among the total population, prevalence of dementia in the group, and social burden for the management of demented patients, dementia must be a public health problem. Neuroscience, which has made an incredible advance applicable to neuropsychiatry during the last few decades, contributes much to gaining new insight into pathophysiology of dementia as well as to its treatment. The early diagnosis of dementia is increasingly important for these reasons. However, it is controversial which of 1) population screening of the elderly, 2) targeting high risk groups, and 3) identification of the elderly with possible mild cognitive impairment is best one . The screening test on the high risk groups and/or the elderly with possible mild cognitive impairment is recommended for the early identification of dementia, with keeping in mind the dementia prevalence, availability of screening tests, possibility of treatment, and social burden resulting from delayed therapeutic intervention.
참고문헌 (36)
- "장래 인구 추계 결과." (2001), 통계청.
- "Henderson AS. The prevalence of dementia a quantitative integration of the literature. Acta Psychiatr Scand 1987", pp.465~79
- "Rates and risk factors for dementia and Alzheimer's disease Results from EURODEM pooled analyses. European Studies of Dementia.", 52, pp.78~84 (1999)
- "Epidemiology of dementia and Alzheimer's disease.", 6, pp.3~18 (1998)
- "C-H Jung. Dementia among the elderly in a rural Korean community. Br J Psychiatry 1994", pp.796~801
- "Prevalence estimation of dementia in a rural area of Korea.", 46, pp.983~987 (1998)
- "한국의 치매 추세와 추계.", 6, pp.79~87 (2002)
- "Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset.", 88, pp.1337~1342 (1998)
- "Looking backward to move forward Early detection of neurodegenerative disorders.", 302, pp.830~834 (2003)
- "Experts from the AMA Dementia Guide. Guide to diagnosis and treatment of dementia." (2003)
- "Screening for dementia: recommendation and rationale.", 138, pp.925~926 (2003)
- "Early diagnosis of dementia.", 63, pp.703~713 (2001)
- "Screening for dementia in primary care a summary of the evidence for the U.S. preventive services task force.", 138, pp.927~937 (2003)
- "인지기능 평가 도구들의 진단 예측치.", 2, pp.78~84 (1998)
- "DeKosky ST. Practice parameter: early detection of dementia: mild cognitive impairment ( an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology.", 56, pp.1133~1142 (2001)
- "Guide to clinical preventive services" (1996), Office of Disease Prevention and Health Promotion
- "Documentation and evaluation of cognitive impairment in elderly primary care patients.", 122, pp.422~429 (1995)
- "Roth M. Do general practitioners miss dementia in elderly patients", pp.1107~10
- "The detection of dementia in the primary care setting.", 160, pp.2964~2968 (2000)
- "Mild cognitive impairment: clinical characterization and outcome.", 56, pp.303~308 (1999)
- "et al. Current concepts in mild cognitive impairment. Arch Neurol 2001" (1985)
- "Mild cognitive impairment predicts dementia in nondemented elderly patients with memory loss.", 58, pp.411~416 (2001)
- "Progression to dementia in patients with isolated memory loss.", 349, pp.763~765 (1997)
- "Mild cognitive impairment represents early- stage Alzheimer's disease.", 58, pp.397~405 (2001)
- "Braak E. Neuropathological staging of Alzheimer- related changes. Acta Neuropathol 1991", pp.239~59
- "Primary progressive pahasia: a rerview of 112 cases.", 60, pp.381~406 (1997)
- "et al. Longitudinal study of cerebral metabolic asymmetries and associated neuropsychological patterns in early dementia of the Alzheimer type. Arch Neurol 1990", pp.753~60
- "Positron emission tomography in evaluation of dementia: regional brain metabolism and long-term outcome.", 286, pp.2120~2127 (2001)
- "Prompt identification of Alzheimer's disease with brain PET imaging of a woman with multiple previous diagnoses of other neuropsychiatric conditions.", 159, pp.1482~1488 (2002)
- "Cerebral glucose metabolism in patients with frontotemporal dementia.", 39, pp.1875~1878 (1998)
- "Kwon YC. Modification of the mini-mental state examination for use in the elderly in a non-westen society. Part I. development of Korean version of mini-mental state examination. Int J Geriatr Psychiatry 1990", pp.381~7
- "간이 기억 검사: 새로운 간편 기억 장애 선별 검사.", 43, pp.337~344 (2004)
- "단축형 Samsung Dementia Questionnaire (S-SDQ)의 개발과 타당도 평가.", 17, pp.253~258 (1999)
- "인지기능 장애 진단 도구: 반구조화 인지기능 평가 도구.", 39, pp.589~597 (2000)
- "Brody EM. Assessment of older people self- maintaining and instrumental activities of daily living. Gerontologist 1969", pp.179~86
- "Jungner G. Principles and practice of screening for disease. Public Health Papers no. 34." (1968)