질병으로서의 흡연
Smoking as a Disease
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참고문헌
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초록
니코틴 중독에 의한 흡연은 조기 사망의 가장 큰 예방 가 능한 원인이 되는 질병이다. 흡연은 담배의 해로움을 알면서 도 충동적으로 사용하게 되는 중독성 질환이며 개별 흡연자 에게 적절한 금연 상담과 진료가 필요하다. 니코틴이 신경전 달물질 분비를 자극하여 의존을 유발하고 금연시에 금단현상 을 유발하게 된다. 금연은 고혈압이나 고지혈증보다 사망률 감소가 크므로 치료가 필요한 질병의 관점에서 접근하는 것 이 필요하다. 중독성 질환으로서 흡연은 흡연 상태와 행동변 화 단계를 확인하고 단계에 맞는 적절한 상담이 금연성공률 을 높일 수 있다. 흡연을 질병의 관점에서 접근하는 최근의 미 국과 일본의 금연진료지침서를 통해 금연 진료의 필요성과 보험급여를 비롯한 정책적 지원을 촉구하고자 한다. 효과적 인 치료가 있으며 국민건강에 영향이 큰 질병인 흡연에 대한 금연진료를 활성화하기위하여 금연진료(상담과 약물)의 보 험 급여가 필요한 시점이다.
Abstract
Smoking is known as one of the major cause of disability and premature death. It should be framed as an individual-level disease requiring medical treatment. Smoking is addictive disease characterized by compulsive drug seeking, and smokers needs therapeutic interventions such as nicotine replacement therapy and nicotine agonist. In terms of addiction, nicotine facilitating neurotransmitter release results in the development of nicotine dependence, and corticotropinreleasing factor related nicotine withdrawal. Smoking will be regarded as disease, for smoking cessation is more effective intervention to prevent mortality than hypertension and dyslipidemia treatment. We will review some aspects of framing tobacco as a disease, and move on to the recent American and Japanese guideline which encourage the social reimbursement system of cessation practice.
참고문헌 (32)
- American Psychiatric Association, "Diagnostic and statistical manual of mental disorders (DSM-IV). 4th ed" (1994), American Psychiatric Association
- Korean Association of Family Medicine, "Health promotion in Korea: smoking", pp.316~358 (2003), GoRyo Pub Co.
- Dani JA, "Molecular and cellular aspects of nicotine abuse", Neuron, 16, pp.905~908 (1996)
- Breslau N, "Nicotine dependence in the United States: prevalence, trends, and smoking persistence", Arch Gen Psychiatry, 58, pp.810~816 (2001)
- Shiffman S, "Individual differences in smoking: gender and nicotine addiction", Nicotine Tob Res, 1(2), pp.S153~S157 (1999)
- Cargill BR, "Relationship among alcohol use, depression, smoking behavior, and motivation to quit smoking with hospitalized smokers", Psychol Addict Behav, 15, pp.272~275 (2001)
- Balfour DJ, "The effects of nicotine on neural pathways implicated in depression: a factor in nicotine addiction?", Pharmacol Biochem Behav, 66, pp.79~85 (2000)
- Glassman AH, "Smoking cessation and the course of major depression: a follow-up study", Lancet, 357, pp.1929~1932 (2001)
- Leonard S, "Smoking and schizophrenia: abnormal nicotinic receptor expression", Eur J Pharmacol, 393, pp.237~242 (2000)
- Patkar AA, "Relationship between tobacco smoking and positive and negative symptoms in schizophrenia", J Nerv Ment Dis, 190, pp.604~610 (2002)
- Koob GF, "Neural mechanisms of drug reinforcement", Ann N Y Acad Sci, 654, pp.171~191 (1992)
- Pontieri FE, "Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs", Nature, 382, pp.255~257 (1996)
- Balfour DJ, "Neural mechanisms underlying nicotine dependence", Addiction, 89, pp.1419~1423 (1994)
- Fowler JS, "Brain monoamine oxidase A inhibition in cigarett e smokers", Proc Natl Acad Sci U S A, 통권 : 93, pp.14065~14069 (1996)
- Grunfeld C, "Metabolic disturbances and wasting in the acquired immunodeficiency syndrome", N Engl J Med, 327, pp.329~337 (1992)
- True WR, "Genetic and environmental contributions to smoking", Addiction, 92, pp.1277~1287 (1997)
- Heath AC, "Genetic models for the natural history of smoking: evidence for a genetic influence on smoking persistence", Addict Behav, 18, pp.19~34 (1993)
- Munafo M, "New directions in the genetic mechanisms underlying nicotine addiction", Addict Biol, 6, pp.109~117 (2001)
- Tyndale RF, "Variable CYP2A6-mediated nicotine metabolism alters smoking behavior and risk", Drug Metab Dispos, 29, pp.548~552 (2001)
- Comings DE, "The dopamine D2 receptor (DRD2) gene: a genetic risk factor in smoking", Pharmacogenetics, 6, pp.73~79 (1996)
- Ishikawa H, "Association between serotonin transporter gene polymorphism and smoking among Japanese males", Cancer Epidemiol Biomarkers Prev, 8, pp.831~833 (1999)
- Lerman C, "Evidence suggesting the role of specific genetic factors in cigarette smoking", Health Psychol, 18, pp.14~20 (1999)
- Benowitz NL, "Non-nicotine pharmacotherapy for smoking cessation: mechanisms and prospects", CNS Drugs, 13, pp.265~285 (2000)
- Covey LS, "Advances in non-nicotine pharmacotherapy for smoking cessation", Drugs, 59, pp.17~31 (2000)
- Stead LF, "Physician advice for smoking cessation", Cochrane Database Syst Rev, (2), pp.CD000165~ (2008)
- Cahill K, "Nicotine receptor partial agonists for smoking cessation", Cochrane Database Syst Rev, (3), pp.CD006103~ (2008)
- Stead LF, "Nicotine replacement therapy for smoking cessation", Cochrane Database Syst Rev, (1), pp.CD000146~ (2008)
- Hughes JR, "Antidepressants for smoking cessation", Cochrane Database Syst Rev, (1), pp.CD000031~ (2007)
- Abbot NC, "Hypnotherapy for smoking cessation", Cochrane Database Syst Rev, (2), pp.CD001008~ (2000)
- White AR, "Acupuncture and related interventions for smoking cessation", Cochrane Database Syst Rev, (1), pp.CD000009~ (2006)
- Clinical Practice Guideline Treating Tobacco Use and Dependence 2008 Update Panel, Liaisons, and Staff, "A clinical practice guideline for treating tobacco use and dependence: 2008 update: a U.S. Public Health Service report", Am J Prev Med, 35, pp.158~176 (2008)
- Japanese Society of Cardiology, "Guideline for smoking cessation. 3rd ed" (2008), Japanese Ministry of Health & Labor