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The Relationship between Serum Gammaglutamyltransferase Level and Overweight in Korean Urban Children

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Background: Recently, it has been reported that gamma-glumyltransferase (GGT) is associated with various cardiovascular risk factors including overweight in adults. However, there are few studies on the relationship between GGT and cardiovascular risk factors in children. The aim of this study was to assess the relationship between serum GGT level and overweight in Korean urban children. Methods: This study was a cross-sectional study using data on 390 4th grade students of elementary schools in Gunpo,Korea. Children were divided into 4 groups according to gender-specifi c quartiles of serum GGT level. Body mass index,waist circumference and body fat percentage were quantifi ed as adiposity indices. Results: All adiposity indices in children of the highest GGT level quartile were higher than those in children of the lowest quartile. Adjusted odd ratios on overweight of the highest quartile of GGT level compared to the lowest quartile were 14.40 (95% confi dence interval [CI], 4.43 to 46.83) in boys and 2.94 (95% CI, 1.06 to 8.16) in girls. Conclusion: This study shows that high serum GGT level is related with overweight in Korean urban children and this relationship is stronger in boys compared to girls.

Abstract

Background: Recently, it has been reported that gamma-glumyltransferase (GGT) is associated with various cardiovascular risk factors including overweight in adults. However, there are few studies on the relationship between GGT and cardiovascular risk factors in children. The aim of this study was to assess the relationship between serum GGT level and overweight in Korean urban children. Methods: This study was a cross-sectional study using data on 390 4th grade students of elementary schools in Gunpo,Korea. Children were divided into 4 groups according to gender-specifi c quartiles of serum GGT level. Body mass index,waist circumference and body fat percentage were quantifi ed as adiposity indices. Results: All adiposity indices in children of the highest GGT level quartile were higher than those in children of the lowest quartile. Adjusted odd ratios on overweight of the highest quartile of GGT level compared to the lowest quartile were 14.40 (95% confi dence interval [CI], 4.43 to 46.83) in boys and 2.94 (95% CI, 1.06 to 8.16) in girls. Conclusion: This study shows that high serum GGT level is related with overweight in Korean urban children and this relationship is stronger in boys compared to girls.

참고문헌 (30)

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