형질전환작물의 위해성평가와 품종등록
Risk assessment and variety registration of transgenic crops
1
조회
0
다운로드
12
인용
0
참고문헌
초록
Final regulatory steps for commercialization of transgenic crops are risk assessment and variety registration. The risk assessment of transgenic crops requires broad network of scientists, high cost and long term. Developers of transgenic crops, therefore, face to additional challenges to consider theoretical and strategic aspects on risk assessment. The general concept for risk assessment of genetically modified organisms was derived from chemical risk assessment. Due to the complexity of organisms, however, comparative approaches that are substantial equivalence and familarity have been developed. In practical view, the integration of risk assessment is more difficult than the evaluation of each risk factors involving gene flow, toxicity and allergenicity. Variety registration of transgenic crops requires the results of risk assessment compared with non-GM crops and agronomic data analyzed with standard varieties. For economic and fast commercialization, risk assessment process should combined with condition of cultivation test for variety registration.
Abstract
Final regulatory steps for commercialization of transgenic crops are risk assessment and variety registration. The risk assessment of transgenic crops requires broad network of scientists, high cost and long term. Developers of transgenic crops, therefore, face to additional challenges to consider theoretical and strategic aspects on risk assessment. The general concept for risk assessment of genetically modified organisms was derived from chemical risk assessment. Due to the complexity of organisms, however, comparative approaches that are substantial equivalence and familarity have been developed. In practical view, the integration of risk assessment is more difficult than the evaluation of each risk factors involving gene flow, toxicity and allergenicity. Variety registration of transgenic crops requires the results of risk assessment compared with non-GM crops and agronomic data analyzed with standard varieties. For economic and fast commercialization, risk assessment process should combined with condition of cultivation test for variety registration.
참고문헌 (21)
- 산업자원부 기술표준원, "유전자변형생물체 (GMO)-용어 KSM 10000" (2007)
- Conner A. J., "The release of genetically modified crops into the environment. Part II. Overview of ecological risk assessment", The Plant Journal, 33, pp.19~46 (2003)
- König A., "Assessment of the safety of foods derived from genetically modified (GM) crops", Food Chem Toxicol, 42, pp.1047~1088 (2004)
- Kuiper H. A., "Exploitation of molecular profiling techniques for GM food safety assessment", Curr Opin Biotechnol, 14, pp.238~243 (2003)
- 유전자변형작물의 환경위해성평 가 가이드라인: 제초제저항성, "이근표", 농촌진흥청 농업생명공학연구원, ~ (2006)
- Recombinant DNA Safety Considerations, "OECD", ~ (1986)
- Hill R. A., "General principles for risk assessment of LMO. Lessons from chemical risk assessment", Environ Biosafety Res, 2, pp.81~88 (2003)
- Safety Considerations for Biotechnology: scale-up of crop plants, "OECD", ~ (1993)
- Safety considerations of foods derived by modern biotechnology: concepts and principles, "OECD", ~ (1993)
- Safety aspects of genetically modified foods of plant origin. Report of a joint FAO, "WHO", WHO, pp.2000, ~
- Wachbroit, R., "Risk assessment in genetic engineering. environmental release organisms in : Describing risk", pp.368~377 (1991), McGraw-Hill
- Risk Analysis Framework, "OGTR", ~ (2007)
- 유전자변형생물체 안전관리 관련 규범, "이근표", 농촌진흥청 농업생명공학연구원, ~ (2006)
- Guidance document of the scientific panel on genetically modified organisms for the risk assessment of genetically modified plants and derived food and feed, "EFSA", ~ (2005)
- Kok E., "Comparative safety assessment for biotech crops", Trends in Biotechnology, 21, pp.439~444 (2003)
- Kalaitzandonakes N., "Measuring the costs of biosafety regulation and the potential impacts on biotechnology research and development", ISBR, 2006, 175~179
- Kalaitzandonakes N., "Compliance costs for regulatory approval of new biotech crops", Nature Biotechnology, 25, pp.509~511 (2007)
- HILL R. A., "Conceptualizing risk assessment methodology for genetically modified organisms", Environ Biosafety Res, 4, pp.67~70 (2005)
- Studies on development of safety assessment Method for genetically modified crops, "Park Y. H.", National Institute of Agricultural Biotechnology RDA, ~ (2002)
- Studies on the environmental safety assessment of herbicide tolerant genetically modified rice Iksan 483 and Milyang 204. Biogreen 21 Final report, "Kim D. H.", RDA, ~, pp.No. 2005030103434373 (2006)
- 한지학, "작물형질전환의 현황과 한국내의 발전전망 및 과제", Journal of Plant Biotechnology, 33(3), pp.171~184 (2006), 한국식물생명공학회