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Superior Vena Cava Syndrome Due to Mediastinal Tuberculous Lymphadenitis

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Superior vena cava (SVC) syndrome refers to a medical emergency resulting from compression of the SVC. It re-quires early diagnosis and treatment, and is usually caused by malignant tumors; rarely, mediastinal tuberculous lymphadenitis can cause SVC syndrome. Here, we present a case study of an immunocompetent 61-year-old wom-an who presented with acute onset SVC syndrome and was diagnosed with tuberculous lymphadenitis on thora-cotomy; the symptoms resolved with anti-tuberculosis therapy. This unusual case highlights the importance of the differential diagnosis in patients presenting with acute onset SVC syndrome; a timely diagnosis and appropriate treatment lead to complete recovery.

Abstract

Superior vena cava (SVC) syndrome refers to a medical emergency resulting from compression of the SVC. It re-quires early diagnosis and treatment, and is usually caused by malignant tumors; rarely, mediastinal tuberculous lymphadenitis can cause SVC syndrome. Here, we present a case study of an immunocompetent 61-year-old wom-an who presented with acute onset SVC syndrome and was diagnosed with tuberculous lymphadenitis on thora-cotomy; the symptoms resolved with anti-tuberculosis therapy. This unusual case highlights the importance of the differential diagnosis in patients presenting with acute onset SVC syndrome; a timely diagnosis and appropriate treatment lead to complete recovery.

참고문헌 (10)

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  6. Wilson LD, "Clinical practice : superior vena cava syndrome with malignant causes", N Engl J Med, 356, pp.1862~1869 (2007)
  7. Rice TW, "The superior vena cava syndrome : clinical characteristics and evolving etiology", Medicine (Baltimore), 85, pp.37~42 (2006)
  8. Khan J, "CTguided fine needle aspiration biopsy in the diagnosis of mediastinal tuberculosis", Chest, 106, pp.1329~1332 (1994)
  9. Geake J, "Utility of EBUS-TBNA for diagnosis of mediastinal tuberculous lymphadenitis : a multicentre Australian experience", J Thorac Dis, 7, pp.439~448 (2015)
  10. Minguez C, "Superior vena cava syndrome during the treatment of pulmonary tuberculosis in an HIV-1 infected patient", J Infect, 40, pp.187~189 (2000)

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