Association between Body Fat and Bone Mineral Density in Normal-Weight Middle-Aged Koreans
2
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Background: Osteoporosis and osteopenia are characterized by reduced bone mineral density (BMD) and in-creased fracture risk. Although the risk of fractures is higher in underweight people than in overweight people, the accumulation of body fat (especially abdominal fat) can increase the risk of bone loss. This study aimed to evaluate the association between body fat percentage and BMD in normal-weight middle-aged Koreans.Methods: This study included 1,992 adults (mean age, 48.7 years; 52.9% women). BMD and body fat were measured using dual-energy X-ray absorptiometry. Multiple linear regression analyses and analysis of covariance were used to assess the association between BMD and body fat. Body fat percentage was grouped by cut-off values. The cut-off values were 20.6% and 25.7% for men with a body mass index of 18.5–22.9 kg/m2, while the cut-off values were 33.4% and 36% for women.Results: Body fat percentage tended to be negatively associated with BMD. Increased body fat percentage was associated with reduced BMD in normal-weight middle-aged adults. The effects of body fat percentage on BMD in normal-weight individuals were more pronounced in men than in women.Conclusion: There was a negative correlation between BMD and body fat percentage in middle-aged Korean men and women with normal body weight. This association was stronger in men than in women.
Abstract
Background: Osteoporosis and osteopenia are characterized by reduced bone mineral density (BMD) and in-creased fracture risk. Although the risk of fractures is higher in underweight people than in overweight people, the accumulation of body fat (especially abdominal fat) can increase the risk of bone loss. This study aimed to evaluate the association between body fat percentage and BMD in normal-weight middle-aged Koreans.Methods: This study included 1,992 adults (mean age, 48.7 years; 52.9% women). BMD and body fat were measured using dual-energy X-ray absorptiometry. Multiple linear regression analyses and analysis of covariance were used to assess the association between BMD and body fat. Body fat percentage was grouped by cut-off values. The cut-off values were 20.6% and 25.7% for men with a body mass index of 18.5–22.9 kg/m2, while the cut-off values were 33.4% and 36% for women.Results: Body fat percentage tended to be negatively associated with BMD. Increased body fat percentage was associated with reduced BMD in normal-weight middle-aged adults. The effects of body fat percentage on BMD in normal-weight individuals were more pronounced in men than in women.Conclusion: There was a negative correlation between BMD and body fat percentage in middle-aged Korean men and women with normal body weight. This association was stronger in men than in women.
참고문헌 (13)
- Beck TJ, "Structural adaptation to changing skeletal load in the progression toward hip fragility : the study of osteoporotic fractures", J Bone Miner Res, 16, pp.1108~1119 (2001)
- Lanyon L, "Postmenopausal osteoporosis as a failure of bone’s adaptation to functional loading : a hypothesis", J Bone Miner Res, 16, pp.1937~1947 (2001)
- Katzmarzyk PT, "Relationship between abdominal fat and bone mineral density in white and African American adults", Bone, 50, pp.576~579 (2012)
- Hsu YH, "Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women", Am J Clin Nutr, 83, pp.146~154 (2006)
- Shin D, "Importance of fat mass and lean mass on bone health in men : the fourth Korean National Health and Nutrition Examination Survey(KNHANES IV)", Osteoporos Int, 25, pp.467~474 (2014)
- Kim MK, "Normal weight obesity in Korean adults", Clin Endocrinol(Oxf), 80, pp.214~220 (2014)
- The 4th and 5th Korea National Health and Nutrition Examination Survey (KNHANES IV-2, IV-3, V-1, V-2), 2008-2011: users’ guide for Korea National Health and Nutrition Examination Survey, "Korea Centers for Disease Control and Prevention", Statistics Korea, ~ (2011)
- Braun T, "Pathways for bone loss in inflammatory disease", Curr Osteoporos Rep, 10, pp.101~108 (2012)
- Choi HS, "Relationship between visceral adiposity and bone mineral density in Korean adults", Calcif Tissue Int, 87, pp.218~225 (2010)
- Kim JH, "Fat mass is negatively associated with bone mineral content in Koreans", Osteoporos Int, 23, pp.2009~2016 (2012)
- Blum M, "Leptin, body composition and bone mineral density in premenopausal women", Calcif Tissue Int, 73, pp.27~32 (2003)
- Reid IR, "Volumetric bone density of the lumbar spine is related to fat mass but not lean mass in normal postmenopausal women", Osteoporos Int, 4, pp.362~367 (1994)
- Saarelainen J, "Body fat distribution is associated with lumbar spine bone density independently of body weight in postmenopausal women", Maturitas, 69, pp.86~90 (2011)