Characteristics of Critically Ill COVID-19 Patients in Busan, Republic of Korea
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Background: This study aimed to improve the clinical course of patients through rapid response by analyzing the characteristics of critically ill patients with confirmed coronavirus disease 2019 (COVID-19) in Busan between De-cember 1, 2020, and December 31, 2021.Methods: We divided patients diagnosed with COVID-19 into mild-to-moderate and critical groups based on their clinical severity. The critically ill patients were further sub-divided into delta and delta variant non-epidemic group.Results: The following factors were significantly more frequent in critically ill patients than in patients with mild-to-moderate symptoms: male sex, age ≥60 years, symptoms at the time of diagnosis, and those with underlying dis-eases. The following factors were significantly more common in the non-delta variant epidemic group than in the delta variant epidemic group in critically ill patients: male sex, age ≥60 years, underlying diseases, and not being vaccinated. In the delta variant epidemic group, the duration between confirmation of disease and its progression to critically ill status was significantly shorter than that in the non-delta variant epidemic group.Conclusion: COVID-19 is characterized by the emergence of new variants and repeated epidemics. Therefore, it is necessary to analyze the characteristics of critically ill patients to efficiently distribute and manage medical resourc-es.
Abstract
Background: This study aimed to improve the clinical course of patients through rapid response by analyzing the characteristics of critically ill patients with confirmed coronavirus disease 2019 (COVID-19) in Busan between De-cember 1, 2020, and December 31, 2021.Methods: We divided patients diagnosed with COVID-19 into mild-to-moderate and critical groups based on their clinical severity. The critically ill patients were further sub-divided into delta and delta variant non-epidemic group.Results: The following factors were significantly more frequent in critically ill patients than in patients with mild-to-moderate symptoms: male sex, age ≥60 years, symptoms at the time of diagnosis, and those with underlying dis-eases. The following factors were significantly more common in the non-delta variant epidemic group than in the delta variant epidemic group in critically ill patients: male sex, age ≥60 years, underlying diseases, and not being vaccinated. In the delta variant epidemic group, the duration between confirmation of disease and its progression to critically ill status was significantly shorter than that in the non-delta variant epidemic group.Conclusion: COVID-19 is characterized by the emergence of new variants and repeated epidemics. Therefore, it is necessary to analyze the characteristics of critically ill patients to efficiently distribute and manage medical resourc-es.
참고문헌 (23)
- Lee SW, "Nationwide results of COVID-19 contact tracing in South Korea : individual participant data from an epidemiological survey", JMIR Med Inform, 8, pp.e20992~ (2020)
- (2022)[URL]
- Korea Disease Control and Prevention Agency, "COVID-19 response guideline" (2020), Korea Disease Control and Prevention Agency
- Shen M, "Recent advances and perspectives of nucleic acid detection for coronavirus", J Pharm Anal, 10, pp.97~101 (2020)
- Ryu B, "Global trends and characteristics of the SARS-CoV-2 Delta variant", Public Health Wkly Rep, 14, pp.2354~2365 (2021)
- Richardson S, "Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area", JAMA, 323, pp.2052~2059 (2020)
- Wu Z, "Characteristics of and important lessons from the coronavirus disease 2019(COVID-19)outbreak in China : summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention", JAMA, 323, pp.1239~1242 (2020)
- Arentz M, "Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington State", JAMA, 323, pp.1612~1614 (2020)
- Cummings MJ, "Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City : a prospective cohort study", Lancet, 395, pp.1763~1770 (2020)
- 이승원, "한국 코로나바이러스감염증-19 환자 5,628명의 역학적, 임상적 특성: 전국단위 다기관 관찰 연구", Allergy Asthma & Respiratory Disease, 9(3), pp.136~140 (2021), 대한 소아알레르기 호흡기학회[DOI]
- Jain V, "Predictive symptoms and comorbidities for severe COVID-19 and intensive care unit admission : a systematic review and meta-analysis", Int J Public Health, 65, pp.533~546 (2020)
- Botta M, "Ventilation management and clinical outcomes in invasively ventilated patients with COVID-19(PRoVENT-COVID) : a national, multicentre, observational cohort study", Lancet Respir Med, 9, pp.139~148 (2021)
- Bhatraju PK, "COVID-19 in critically ill patients in the Seattle region : case series", N Engl J Med, 382, pp.2012~2022 (2020)
- Yang X, "Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China : a single-centered, retrospective, observational study", Lancet Respir Med, 8, pp.475~481 (2020)
- Auld SC, "ICU and ventilator mortality among critically ill adults with coronavirus disease 2019", Crit Care Med, 48, pp.e799~e804 (2020)
- Huang C, "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China", Lancet, 395, pp.497~506 (2020)
- Wang D, "Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China", JAMA, 323, pp.1061~1069 (2020)
- Zhou F, "Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China : a retrospective cohort study", Lancet, 395, pp.1054~1062 (2020)
- 2021 Jul 5, "2021", ~
- Public Health England, "SARS-CoV-2 variants of concern and variants under investigation in England" (2021), Public Health England
- Singh C, "Effectiveness of COVID-19 vaccine in preventing infection and disease severity : a case-control study from an Eastern State of India", Epidemiol Infect, 149, pp.e224~ (2021)
- Ryu B, "Severity of COVID-19 associated with SARS-CoV-2 variants circulating in the Republic of Korea", Public Health Wkly Rep, 15, pp.2873~2895 (2022)
- Ritchie JE, "Evaluation of a humidified nasal high-flow oxygen system, using oxygraphy, capnography and measurement of upper airway pressures", Anaesth Intensive Care, 39, pp.1103~1110 (2011)