Preparation and Physical Properties of Silicone Hydrogel Ophthalmic Lens Containing Hydrophilic Monomer
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The major physical characteristics of macromolecules used in silicone hydrogel ophthalmic lenses include optical transmittance, oxygen permeability, water content, and refractive index. For the preparation of highly functional silicone hydrogel lens materials, two silicone monomers were used in the presence of 2-hydroxyethyl methacrylate (HEMA) and hydroxypropyl methacrylate (HPMA). The samples containing HEMA and HPMA had oxygen transmissibility (Dk) values in the range of 73.38–50.98 × 10-11 (cm2/s) (mLO2/mL×mmHg) and 71.94–42.80 × 10-11 (cm2/s) (mLO2/mL×mmHg), respectively. Furthermore, the water contents of samples containing HEMA and HPMA were in the range of 32.73–34.67% and 31.94–33.74%, respectively, and the refractive indices were in the range of 1.4348–1.4364 and 1.4385–1.4407, respectively. Thus, silicone monomers containing HEMA and HPMA are expected to be useful for fabricating high-oxygen-permeability silicon hydrogel ophthalmic lenses.
Abstract
The major physical characteristics of macromolecules used in silicone hydrogel ophthalmic lenses include optical transmittance, oxygen permeability, water content, and refractive index. For the preparation of highly functional silicone hydrogel lens materials, two silicone monomers were used in the presence of 2-hydroxyethyl methacrylate (HEMA) and hydroxypropyl methacrylate (HPMA). The samples containing HEMA and HPMA had oxygen transmissibility (Dk) values in the range of 73.38–50.98 × 10-11 (cm2/s) (mLO2/mL×mmHg) and 71.94–42.80 × 10-11 (cm2/s) (mLO2/mL×mmHg), respectively. Furthermore, the water contents of samples containing HEMA and HPMA were in the range of 32.73–34.67% and 31.94–33.74%, respectively, and the refractive indices were in the range of 1.4348–1.4364 and 1.4385–1.4407, respectively. Thus, silicone monomers containing HEMA and HPMA are expected to be useful for fabricating high-oxygen-permeability silicon hydrogel ophthalmic lenses.
참고문헌 (14)
- 지용우, "미세표면분석 기법을 이용한 미용 콘택트렌즈와 일반 콘택트렌즈의 표면거칠기와 세균부착성 비교", 대한안과학회지, 55(5), pp.646~655 (2014), 대한안과학회
- Efron, N., , Optom. Vis. Sci, 89, pp.122~ (2012)
- Morgan, P. B., , Eye & Contact Lens, 39, pp.200~ (2013)
- Efron, N., , Clin. Exp. Optom, 96, pp.58~ (2013)
- 김태훈, "미용 칼라 콘택트렌즈의 습윤성에 관한 연구", 대한시과학회지, 12(2), pp.119~125 (2010), 대한시과학회
- 예기훈, "소수성 모노머들을 포함한 콘택트렌즈의 특성에 관한 연구", 한국안광학회지, 13(3), pp.29~34 (2008), 한국안광학회
- Steinemann, T. L., , Eye & Contact Lens, 29(4), pp.196~ (2003)
- Gellatly, K. W., , Am. J. Optom-etry Physiol. Opt, 65, pp.934~ (1988)
- 김태훈, "HEMA가 치환된 Polyphosphazene의 공중합 및 콘택트렌즈 응용", 대한화학회지, 53(3), pp.340~344 (2009), 대한화학회
- Allcock, H. R., , Sci. Prog. Oxf. 1, 66, pp.355~ (1980)
- Laurencin, C. T., , J. Biomed. Mat. Res, 27, pp.963~ (1993)
- Lskshmi, S., , Adv. Drug Delivery Rev, 55, pp.467~ (2002)
- 성아영, "산소투과성이 뛰어난 hydrogel 콘택트렌즈 합성", 한국안광학회지, 11(1), pp.49~53 (2006), 한국안광학회
- Maldonado-Codina, C, , Efron, N. Optometry in Practice, 4, pp.101~ (2003)