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A 12-Year Retrospective Study of Survival Rates and Out- comes of Very Low Birth Weight Infants in a Single Center

신손문|이연경|고선영|Moon Sun Jeong|Seok Ho Yoon
대한신생아학회 (THE KOREAN SOCIETY OF NEONATOLOGY)|2016.02|Neonatal medicine|제23권 제1호|pp. 1-7

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키워드

InfantOutcomeVery low birth weight

초록

Purpose: To investigate the outcomes and survival rates of very low birth weight infants (VLBWI) born over a 12-year period in a single center. Methods: A retrospective review of 613 VLBWI born from January 2000 to December 2011 was performed. We compared the incidence, survival rate, and morbidity of infants classified according to their birth weight or gestational age for the following periods: Period I (2000-2002), Period II (2003-2005), Period III (2006-2008), and Period IV (2009-2011). Results: The incidence of VLBWI was 0.7%, while the overall survival rate was 94.9%. The survival rates were 92.8%, 92.9%, 95.9%, and 97.5% for periods I, II, III and IV, res- pectively; the rates improved significantly over time (P<0.05). The average survival rate of extremely low birth weight infants was 85.9%, and it tended to increase over successive periods (P=0.06). The overall incidence of respiratory distress syndrome was 63.6%; patent ductus arteriosus; 43.6%; bronchopulmonary dysplasia, 30.5%; retinopathy of prematurity (≥grade III), 8.5%; sepsis, 6.5%; cystic periventricular leukomalacia, 3.8%; necrotizing enterocolitis (≥grade II), 3.4%; and intraventricular hemorrhage (≥grade III), 2.3%. A significant decrease was seen in some clinical para- meters: the time to start feeding, duration of parenteral nutrition, and duration re- quired to reach full enteral feeding in every successive three-year period (P<0.01). Conclusion: The overall survival rate of VLBWI born between January 2000 and December 2011 was 94.9%. This survival rate was found to increase significantly in each successive three-year period starting January 2000.

Abstract

Purpose: To investigate the outcomes and survival rates of very low birth weight infants (VLBWI) born over a 12-year period in a single center. Methods: A retrospective review of 613 VLBWI born from January 2000 to December 2011 was performed. We compared the incidence, survival rate, and morbidity of infants classified according to their birth weight or gestational age for the following periods: Period I (2000-2002), Period II (2003-2005), Period III (2006-2008), and Period IV (2009-2011). Results: The incidence of VLBWI was 0.7%, while the overall survival rate was 94.9%. The survival rates were 92.8%, 92.9%, 95.9%, and 97.5% for periods I, II, III and IV, res- pectively; the rates improved significantly over time (P<0.05). The average survival rate of extremely low birth weight infants was 85.9%, and it tended to increase over successive periods (P=0.06). The overall incidence of respiratory distress syndrome was 63.6%; patent ductus arteriosus; 43.6%; bronchopulmonary dysplasia, 30.5%; retinopathy of prematurity (≥grade III), 8.5%; sepsis, 6.5%; cystic periventricular leukomalacia, 3.8%; necrotizing enterocolitis (≥grade II), 3.4%; and intraventricular hemorrhage (≥grade III), 2.3%. A significant decrease was seen in some clinical para- meters: the time to start feeding, duration of parenteral nutrition, and duration re- quired to reach full enteral feeding in every successive three-year period (P<0.01). Conclusion: The overall survival rate of VLBWI born between January 2000 and December 2011 was 94.9%. This survival rate was found to increase significantly in each successive three-year period starting January 2000.

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