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Liver Abscess Associated with Maternal Perinatal Infection in a Premature Infant

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초록

Neonatal liver abscesses are rare, carry a high mortality rate, and are difficult to diagnose. The diagnosis of liver abscesses in the neonate cannot be established from the clinical presentation alone. Risk factors for liver abscesses in neonates are maternal infection, sepsis, umbilical venous catheterization, omphalitis, and necrotizing enterocolitis. In this report, we describe a preterm infant (32 weeks, 1,580 g) who presented with abdominal distension, respiratory difficulties, and a persistent inflammatory response in spite of broad spectrum antibiotic treatment; a large (6×5 cm) solitary pyogenic liver abscess was identified at 9 days of age. It appeared that the liver abscess had originated in the uterus and umbilical venous catheterization facilitated its spread. Percutaneous drainage under abdominal ultrasound guidance was performed and prolonged antibiotics were treated for 5 weeks, effecting a cure.

Abstract

Neonatal liver abscesses are rare, carry a high mortality rate, and are difficult to diagnose. The diagnosis of liver abscesses in the neonate cannot be established from the clinical presentation alone. Risk factors for liver abscesses in neonates are maternal infection, sepsis, umbilical venous catheterization, omphalitis, and necrotizing enterocolitis. In this report, we describe a preterm infant (32 weeks, 1,580 g) who presented with abdominal distension, respiratory difficulties, and a persistent inflammatory response in spite of broad spectrum antibiotic treatment; a large (6×5 cm) solitary pyogenic liver abscess was identified at 9 days of age. It appeared that the liver abscess had originated in the uterus and umbilical venous catheterization facilitated its spread. Percutaneous drainage under abdominal ultrasound guidance was performed and prolonged antibiotics were treated for 5 weeks, effecting a cure.

참고문헌 (12)

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  7. Moss TJ, "Hepatic abscess in neonates", Am J Dis Child, 135, pp.726~728 (1981)
  8. Maruyama K, "Solitary liver abscess caused by methicillin-resistent Staphylococcus aureus in a very low birth weight infant", Pediatr Int, 42, pp.380~382 (2000)
  9. Seo HJ, "Two cases of solitary liver abscess in preterm infant suspiciously caused by umbilical venous catheter", J Korean Soc Neonatol, 13, pp.267~272 (2006)
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  12. Sharma S, "Hepatic abscess in a preterm neonate", Indian Pediatr, 44, pp.226~228 (2007)

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