Successful Treatment of Neonatal Pylorospasm with Intravenous Atropine
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Pylorospasm is a cause of delayed gastric emptying in young infants. As in patients with hypertrophic pyloric stenosis, most pylorospasm patients present with projectile vomiting. However, unlike that in case of hypertrophic pyloric stenosis, no persistent pyloric stenotic lesions are present. As such, follow-up using serial gastrointestinal fluoroscopy or ultrasonography can be helpful in diagnosing patients with clinical signs of gastroparesis. Most cases can be treated conservatively, but some patients require pharmacologic treatment. Antispasmodics have been proposed as a treatment for pylorospasm, but their use in neonates and infants has rarely been reported. Herein, we present a case of pylorospasm diagnosed in the neonatal period and successfully treated with intravenous atropine.
Abstract
Pylorospasm is a cause of delayed gastric emptying in young infants. As in patients with hypertrophic pyloric stenosis, most pylorospasm patients present with projectile vomiting. However, unlike that in case of hypertrophic pyloric stenosis, no persistent pyloric stenotic lesions are present. As such, follow-up using serial gastrointestinal fluoroscopy or ultrasonography can be helpful in diagnosing patients with clinical signs of gastroparesis. Most cases can be treated conservatively, but some patients require pharmacologic treatment. Antispasmodics have been proposed as a treatment for pylorospasm, but their use in neonates and infants has rarely been reported. Herein, we present a case of pylorospasm diagnosed in the neonatal period and successfully treated with intravenous atropine.
참고문헌 (9)
- Gilet AG, "Pylorospasm (simulating hypertrophic pyloric stenosis) with secondary gastroesophageal reflux", Ultrasound Q, 24, pp.93~96 (2008)
- Cohen HL, "Ultrasonography of pylorospasm: findings may simulate hypertrophic pyloric stenosis", J Ultrasound Med, 17, pp.705~711 (1998)
- Cohen HL, "The sonographic doubletrack sign: not pathognomonic for hypertrophic pyloric stenosis;can be seen in pylorospasm", J Ultrasound Med, 23, pp.641~646 (2004)
- Islam S., "Gastroparesis in children", Curr Opin Pediatr, 27, pp.377~382 (2015)
- Tillman EM, "Pharmacologic treatment for pediatric gastroparesis: a review of the literature", J Pediatr Pharmacol Ther, 21, pp.120~132 (2016)
- Heidelbaugh JJ, "Gastrointestinal diseases: a multidisciplinary approach", pp.309~ (2015), Elsevier Health Science
- Hilas O., "Management of gastroparesis", US Pharm, 36, pp.HS15~HS18 (2011)
- Lauriti G, "Atropine treatment for hypertrophic pyloric stenosis: a systematic review and meta-analysis", Eur J Pediatr Surg, 28, pp.393~399 (2018)
- Wu SF, "Efficacy of medical treatment for infantile hypertrophic pyloric stenosis:a meta-analysis", Pediatr Neonatol, 57, pp.515~521 (2016)