Effect of Repetitive Transcranial Magnetic Stimulation on Post-stroke Non-fluent Aphasia in Relation with Broca's Area
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This study investigated the differences in the effect of repetitive transcranial magnetic stimulation (rTMS) between patients with and without the involvement of Broca's area (IBA). The medical records of 20 stroke patients treated with rTMS for non-fluent aphasia were reviewed. Patients completed the Korean version of the Western Aphasia Battery (K-WAB) pre- and post-rTMS. Magnetic resonance T1-weighted images of the brain were analyzed using SPM12 software. Montreal Neurological Institute templates and Talairach coordinates were used to determine Broca's area involvement and segregate patients into 2 groups: IBA and non-IBA (NBA) groups. All statistical analyses were performed using the SPSS software. Twenty subjects were included in the study. The K-WAB scores revealed improvements in the total subjects and IBA and NBA groups. There were no statistical differences between the IBA and NBA groups in the ΔK-WAB scores of aphasia quotient, fluency, comprehension, repetition, and naming. The rTMS was positive for non-fluent aphasia patients, but there was no significant difference in effectiveness depending on the IBA. Further research with a larger number of patients is needed to identify the differences in the effect of rTMS on the IBA.
Abstract
This study investigated the differences in the effect of repetitive transcranial magnetic stimulation (rTMS) between patients with and without the involvement of Broca's area (IBA). The medical records of 20 stroke patients treated with rTMS for non-fluent aphasia were reviewed. Patients completed the Korean version of the Western Aphasia Battery (K-WAB) pre- and post-rTMS. Magnetic resonance T1-weighted images of the brain were analyzed using SPM12 software. Montreal Neurological Institute templates and Talairach coordinates were used to determine Broca's area involvement and segregate patients into 2 groups: IBA and non-IBA (NBA) groups. All statistical analyses were performed using the SPSS software. Twenty subjects were included in the study. The K-WAB scores revealed improvements in the total subjects and IBA and NBA groups. There were no statistical differences between the IBA and NBA groups in the ΔK-WAB scores of aphasia quotient, fluency, comprehension, repetition, and naming. The rTMS was positive for non-fluent aphasia patients, but there was no significant difference in effectiveness depending on the IBA. Further research with a larger number of patients is needed to identify the differences in the effect of rTMS on the IBA.
참고문헌 (26)
- Annual report on the causes of death statistics, "Statistics Korea", Statistics Korea, ~ (2019)
- Skilbeck CE, "Recovery after stroke", J Neurol Neurosurg Psychiatry, 46, pp.5~8 (1983)
- Flowers HL, "Poststroke aphasia frequency, recovery, and outcomes : a systematic review and meta-analysis", Arch Phys Med Rehabil, 97, pp.2188~2201 (2016)[DOI]
- Brady MC, "Speech and language therapy for aphasia following stroke", Cochrane Database Syst Rev, 2016, pp.CD000425~ (2016)
- Berthier ML, "Drug therapy of post-stroke aphasia : a review of current evidence", Neuropsychol Rev, 21, pp.302~317 (2011)
- Lefaucheur JP, "Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation(rTMS)", Clin Neurophysiol, 125, pp.2150~2206 (2014)
- Lefaucheur JP, "Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation(rTMS) : an update(2014–2018)", Clin Neurophysiol, 131, pp.474~528 (2020)
- Maeda F, "Interindividual variability of the modulatory effects of repetitive transcranial magnetic stimulation on cortical excitability", Exp Brain Res, 133, pp.425~430 (2000)
- Brown JA, "Motor cortex stimulation for enhancement of recovery after stroke : case report", Neurol Res, 25, pp.815~818 (2003)
- Ren CL, "Effect of lowfrequency rTMS on aphasia in stroke patients : a meta-analysis of randomized controlled trials", PLoS One, 9, pp.e102557~ (2014)
- Hu XY, "Effects of different frequencies of repetitive transcranial magnetic stimulation in stroke patients with non-fluent aphasia : a randomized, sham-controlled study", Neurol Res, 40, pp.459~465 (2018)
- Yoon TH, "Therapeutic effect of repetitive magnetic stimulation combined with speech and language therapy in post-stroke non-fluent aphasia", NeuroRehabilitation, 36, pp.107~114 (2015)
- Watila MM, "Factors predicting post-stroke aphasia recovery", J Neurol Sci, 352, pp.12~18 (2015)
- Hanlon RE, "Global aphasia without hemiparesis : language profiles and lesion distribution", J Neurol Neurosurg Psychiatry, 66, pp.365~369 (1999)
- Kertesz A, "The structural determinants of recovery in Wernicke’s aphasia", Brain Lang, 44, pp.153~164 (1993)
- Bomi Sul, "The Prognosis and Recovery of Aphasia Related to Stroke Lesion", Annals of Rehabilitation Medicine, 40(5), pp.786~793 (2016), 대한재활의학회
- Foundas AL, "MRI asymmetries of Broca's area : the pars triangularis and pars opercularis", Brain Lang, 64, pp.282~296 (1998)
- Touryan SR, "The influence of selfregulatory focus on encoding of, and memory for, emotional words", Soc Neurosci, 2, pp.14~27 (2007)
- Kim H, "Normative data on the Korean version of the Western aphasia battery", J Clin Exp Neuropsychol, 26, pp.1011~1020 (2004)
- Shewan CM, "Reliability and validity characteristics of the Western aphasia battery(WAB)", J Speech Hear Disord, 45, pp.308~324 (1980)
- Kertesz A, "Western aphasia battery test manual", Psychological Corp, ~ (1982)
- Kertesz A, "The aphasia quotient : the taxonomic approach to measurement of aphasic disability", Can J Neurol Sci, 1, pp.7~16 (1974)
- Waldowski K, "Effect of low-frequency repetitive transcranial magnetic stimulation on naming abilities in early-stroke aphasic patients : a prospective, randomized, double-blind sham-controlled study", Sci World J, 2012, pp.518568~ (2012)
- Tsai PY, "The persistent and broadly modulating effect of inhibitory rTMS in nonfluent aphasic patients : a sham-controlled, double-blind study", Neurorehabil Neural Repair, 28, pp.779~787 (2014)
- Hsu WY, "Effects of repetitive transcranial magnetic stimulation on motor functions in patients with stroke : a meta-analysis", Stroke, 43, pp.1849~1857 (2012)
- Zumbansen A, "Non-invasive brain stimulation as add-on therapy for subacute post-stroke aphasia : a randomized trial(NORTHSTAR)", Eur Stroke J, 5, pp.402~413 (2020)