Sick Sinus Syndrome Combined with Wallenberg Syndrome: a Case Report
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Cardiac arrhythmia is a rare manifestation of the Wallenberg syndrome; lesions are located in the brainstem, especially the lower medulla, which regulates sympathetic and parasympathetic activity. A 55-year-old man was admitted to the university hospital with symptoms including ataxia, left ptosis, decreased sensation of pain and temperature on the right side, left facial numbness, and dizziness. Brain magnetic resonance imaging revealed an infarction in the left dorsolateral medulla. Therefore, he was diagnosed with Wallenberg syndrome. While he underwent conservative treatment for Wallenberg syndrome, he experienced several events of self-limiting heart pounding, which required an evaluation of cardiac function. The 24-hour Holter monitor showed an increased RR interval with bradycardia and prolonged sinus pause. As a result, the diagnosis of sick sinus syndrome combined with Wallenberg syndrome was made. Sick sinus syndrome is a rare cardiac complication of the Wallenberg syndrome, and clinicians could overlook it when the initial electrocardiography shows a normal sinus rhythm. Sick sinus syndrome can cause sudden death without appropriate medical intervention. Therefore, clinicians should consider further evaluation, including a 24-hour Holter monitor, to check for the potential presence of sick sinus syndrome in the acute phase of Wallenberg syndrome.
Abstract
Cardiac arrhythmia is a rare manifestation of the Wallenberg syndrome; lesions are located in the brainstem, especially the lower medulla, which regulates sympathetic and parasympathetic activity. A 55-year-old man was admitted to the university hospital with symptoms including ataxia, left ptosis, decreased sensation of pain and temperature on the right side, left facial numbness, and dizziness. Brain magnetic resonance imaging revealed an infarction in the left dorsolateral medulla. Therefore, he was diagnosed with Wallenberg syndrome. While he underwent conservative treatment for Wallenberg syndrome, he experienced several events of self-limiting heart pounding, which required an evaluation of cardiac function. The 24-hour Holter monitor showed an increased RR interval with bradycardia and prolonged sinus pause. As a result, the diagnosis of sick sinus syndrome combined with Wallenberg syndrome was made. Sick sinus syndrome is a rare cardiac complication of the Wallenberg syndrome, and clinicians could overlook it when the initial electrocardiography shows a normal sinus rhythm. Sick sinus syndrome can cause sudden death without appropriate medical intervention. Therefore, clinicians should consider further evaluation, including a 24-hour Holter monitor, to check for the potential presence of sick sinus syndrome in the acute phase of Wallenberg syndrome.
참고문헌 (13)
- Sacco RL, "Wallenberg's lateral medullary syndrome. Clinical-magnetic resonance imaging correlations", Arch Neurol, 50, pp.609~614 (1993)
- Semelka M, "Sick sinus syndrome : a review", Am Fam Physician, 87, pp.691~696 (2013)
- Reis DJ, "Evidence that glutamic acid is the neurotransmitter of baroreceptor afferent terminating in the nucleus tractus solitarius(NTS)", J Auton Nerv Syst, 3, pp.321~334 (1981)
- Abdala AP, "Ablation of NK1 receptor bearing neurons in the nucleus of the solitary tract blunts cardiovascular reflexes in awake rats", Brain Res, 1119, pp.165~173 (2006)
- Biaggioni I, "Baroreflex failure in a patient with central nervous system lesions involving the nucleus tractus solitarii", Hypertension, 23, pp.491~495 (1994)
- Brown S, "Cardiovascular actions of adrenocorticotropin microinjections into the nucleus tractus solitarius of the rat", Neuroscience, 143, pp.863~874 (2006)
- Biondo B, "Glial and neuronal alterations in the nucleus tractus solitarii of sudden infant death syndrome victims", Acta Neuropathol, 109, pp.552~553 (2005)
- De Caro R, "Solitary tract nuclei in acute heart failure", Stroke, 31, pp.1187~1193 (2000)
- Meglic B, "Autonomic nervous system function in patients with acute brainstem stroke", Cerebrovasc Dis, 11, pp.2~8 (2001)
- Koay S, "An unexpected Holter monitor result : multiple sinus arrests in a patient with lateral medullary syndrome", BMJ Case Rep (2013)
- Takazawa T, "A case of sinus arrest and post-hiccup cough syncope in medullary infarction", J Stroke Cerebrovasc Dis, 23, pp.566~571 (2014)
- von Heinemann P, "Recurrent cardiac arrest caused by lateral medulla oblongata infarction", BMJ Case Rep, 2009 (2009)[DOI]
- Huynh TR, "Lateral medullary infarction with cardiovascular autonomic dysfunction : an unusual presentation with review of the literature", Clin Auton Res, 28, pp.569~576 (2018)
