본문 바로가기
KERD
논문KCI 등재

Nutrition Management in Patients With Traumatic Brain Injury: A Narrative Review

2

조회

0

다운로드

1

인용

0

참고문헌

키워드

초록

Traumatic brain injury (TBI) is a major cause of long-term physical and psychological disability and death. In patients with TBI, undernutrition is associated with an increased mortality rate, more infectious complications, and worse neurologic outcomes. Therefore, timely and effective nutritional therapy is particularly crucial in the management of TBI to improve patients’ prognoses. This narrative review summarizes the issues encountered in clinical practice for patients with neurotrauma who receive acute and post-acute in-patient rehabilitation services, and it comprehensively incorporates a wide range of studies, including recent clinical practice guidelines (CPGs), with the aim of better understanding the current evidence for optimal nutritional therapy focused on TBI patients. Recent CPGs were reviewed for 6 topics: 1) hypermetabolism and variation in energy expenditure in patients with TBI, 2) delayed gastric emptying and intolerance to enteral nutrition, 3) decision-making on the route and timing of access in patients with TBI who are unable to maintain volitional intake (enteral nutrition versus parenteral nutrition), 4) decision-making on the enteral formula (standard or immune-modulating formulas), 5) glycemic control, and 6) protein support. We also identified areas that need further research in the future.

Abstract

Traumatic brain injury (TBI) is a major cause of long-term physical and psychological disability and death. In patients with TBI, undernutrition is associated with an increased mortality rate, more infectious complications, and worse neurologic outcomes. Therefore, timely and effective nutritional therapy is particularly crucial in the management of TBI to improve patients’ prognoses. This narrative review summarizes the issues encountered in clinical practice for patients with neurotrauma who receive acute and post-acute in-patient rehabilitation services, and it comprehensively incorporates a wide range of studies, including recent clinical practice guidelines (CPGs), with the aim of better understanding the current evidence for optimal nutritional therapy focused on TBI patients. Recent CPGs were reviewed for 6 topics: 1) hypermetabolism and variation in energy expenditure in patients with TBI, 2) delayed gastric emptying and intolerance to enteral nutrition, 3) decision-making on the route and timing of access in patients with TBI who are unable to maintain volitional intake (enteral nutrition versus parenteral nutrition), 4) decision-making on the enteral formula (standard or immune-modulating formulas), 5) glycemic control, and 6) protein support. We also identified areas that need further research in the future.

참고문헌 (65)

  1. GBD 2016 Traumatic Brain Injury and Spinal Cord Injury Collaborators, "Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990-2016 : a systematic analysis for the Global Burden of Disease Study 2016", Lancet Neurol, 18, pp.56~87 (2019)
  2. Lee Ye Seol, "The Socioeconomic Burden of Acquired Brain Injury among the Korean Patients over 20 Years of Age in 2015–2017: a Prevalence-Based Approach", 뇌신경재활, 14(3), pp.1~15 (2021), 대한뇌신경재활학회[DOI]
  3. Kim HK, "Decreasing incidence and mortality in traumatic brain injury in Korea, 2008–2017 : a population-based longitudinal study", Int J Environ Res Public Health, 17, pp.6197~ (2020)
  4. 김한결, "Epidemiological Trends and Rehabilitation Utilization of Traumatic Brain Injury in Korea (2008–2018)", 뇌신경재활, 14(3), pp.1~10 (2021), 대한뇌신경재활학회[DOI]
  5. Tavarez T, "Nutrition in the neurocritical care unit : a new frontier", Curr Treat Options Neurol, 23, pp.16~ (2021)
  6. Quintard H, "Nutritional and metabolic supplementation for the injured brain : an update", Curr Opin Crit Care, 25, pp.126~131 (2019)
  7. Krakau K, "Metabolism and nutrition in patients with moderate and severe traumatic brain injury : a systematic review", Brain Inj, 20, pp.345~367 (2006)
  8. Kurtz P, "Nutrition therapy, glucose control, and brain metabolism in traumatic brain injury : a multimodal monitoring approach", Front Neurosci, 14, pp.190~ (2020)
  9. Bjørklund G, "Role of oxidative stress and antioxidants in daily nutrition and human health", Nutrition, 33, pp.311~321 (2017)
  10. Markovic SJ, "The impact of exercise, sleep, and diet on neurocognitive recovery from mild traumatic brain injury in older adults : a narrative review", Ageing Res Rev, 68, pp.101322~ (2021)
  11. Oddo M, "Boosting the injured brain with supplemental energy fuels", Intensive Care Med, 45, pp.872~875 (2019)
  12. Ho Joong Jung, "Suggested Assessments for Sarcopenia in Patients With Stroke Who Can Walk Independently", Annals of Rehabilitation Medicine, 44(1), pp.20~37 (2020), 대한재활의학회[DOI]
  13. Jin Hwa Yi, "Bowel Function in Acute Stroke Patients", Annals of Rehabilitation Medicine, 35(3), pp.337~343 (2011), 대한재활의학회
  14. Krakau K, "Nutritional treatment of patients with severe traumatic brain injury during the first six months after injury", Nutrition, 23, pp.308~317 (2007)
  15. Faisy C, "Assessment of resting energy expenditure in mechanically ventilated patients", Am J Clin Nutr, 78, pp.241~249 (2003)
  16. Zasler ND, "Brain injury medicine:principles and practice", pp.902~911 (2012), Demos Medical Publishing
  17. McClave SA, "Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)", JPEN J Parenter Enteral Nutr, 40, pp.159~211 (2016)
  18. Frankenfield D, "Validation of 2 approaches to predicting resting metabolic rate in critically ill patients", JPEN J Parenter Enteral Nutr, 28, pp.259~264 (2004)
  19. Graf S, "Evaluation of three indirect calorimetry devices in mechanically ventilated patients: which device compares best with the Deltatrac II®? A prospective observational study", Clin Nutr, 34, pp.60~65 (2015)
  20. Cook AM, "Nutrition considerations in traumatic brain injury", Nutr Clin Pract, 23, pp.608~620 (2008)
  21. Lee SJ, "Comparison of measured energy expenditure using indirect calorimetry vs predictive equations for liver transplant recipients", JPEN J Parenter Enteral Nutr, 45, pp.761~767 (2021)
  22. Carney N, "Guidelines for the management of severe traumatic brain injury", Neurosurgery, 80, pp.6~15 (2017)
  23. Ott L, "Altered gastric emptying in the head-injured patient : relationship to feeding intolerance", J Neurosurg, 74, pp.738~742 (1991)
  24. Kao CH, "Gastric emptying in head-injured patients", Am J Gastroenterol, 93, pp.1108~1112 (1998)
  25. Gore RM, "Gastrointestinal complications of spinal cord injury", Spine, 6, pp.538~554 (1981)
  26. Abdelmalik PA, "Nutritional and bioenergetic considerations in critically ill patients with acute neurological injury", Neurocrit Care, 27, pp.276~286 (2017)
  27. Chapple LA, "Nutrition support practices in critically ill head-injured patients : a global perspective", Crit Care, 20, pp.6~ (2015)
  28. Kattelmann KK, "Preliminary evidence for a medical nutrition therapy protocol : enteral feedings for critically ill patients", J Am Diet Assoc, 106, pp.1226~1241 (2006)
  29. Mazaherpur S, "The effect of continuous enteral nutrition on nutrition indices, compared to the intermittent and combination enteral nutrition in traumatic brain injury patients", J Clin Diagn Res, 10, pp.JC01~JC05 (2016)
  30. Dickerson RN, "Disparate response to metoclopramide therapy for gastric feeding intolerance in trauma patients with and without traumatic brain injury", JPEN J Parenter Enteral Nutr, 33, pp.646~655 (2009)
  31. Nursal TZ, "The effect of metoclopramide on gastric emptying in traumatic brain injury", J Clin Neurosci, 14, pp.344~348 (2007)
  32. Singer P, "ESPEN guideline on clinical nutrition in the intensive care unit", Clin Nutr, 38, pp.48~79 (2019)
  33. Heyland DK, "Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients", JPEN J Parenter Enteral Nutr, 27, pp.355~373 (2003)
  34. Marik PE, "Early enteral nutrition in acutely ill patients : a systematic review", Crit Care Med, 29, pp.2264~2270 (2001)
  35. Kang W, "Is there evidence that the gut contributes to mucosal immunity in humans?", JPEN J Parenter Enteral Nutr, 31, pp.246~258 (2007)
  36. Casaer MP, "Early versus late parenteral nutrition in critically ill adults", N Engl J Med, 365, pp.506~517 (2011)
  37. Lacey JM, "Is glutamine a conditionally essential amino acid?", Nutr Rev, 48, pp.297~309 (1990)
  38. Zeng J, "Effects of glutamine-enriched enteral nutrition on nutritional status and prognosis of patients with severe head injury", Zhonghua Shao Shang Za Zhi, 25, pp.335~338 (2009)
  39. Falcão de Arruda IS, "Benefits of early enteral nutrition with glutamine and probiotics in brain injury patients", Clin Sci(Lond), 106, pp.287~292 (2004)
  40. Yang DL, "Effect of dipeptide of glutamine and alanine on severe traumatic brain injury", Chin J Traumatol, 10, pp.145~149 (2007)
  41. Heyland D, "A randomized trial of glutamine and antioxidants in critically ill patients", N Engl J Med, 368, pp.1489~1497 (2013)
  42. Dyall SC, "Long-chain omega-3 fatty acids and the brain : a review of the independent and shared effects of EPA, DPA and DHA", Front Aging Neurosci, 7, pp.52~ (2015)
  43. Bailes JE, "Omega-3 fatty acid supplementation in severe brain trauma : case for a large multicenter trial", J Neurosurg, 133, pp.1~5 (2020)
  44. Sears B, "Therapeutic uses of high-dose omega-3 fatty acids to treat comatose patients with severe brain injury", PharmaNutrition, 1, pp.86~89 (2013)
  45. Noguchi H, "Limited effect of omega-3fatty acids on the quality of life in survivors of traumatic injury : a randomized, placebo-controlled trial", Prostaglandins Leukot Essent Fatty Acids, 127, pp.1~5 (2017)
  46. Hasadsri L, "Omega-3 fatty acids as a putative treatment for traumatic brain injury", J Neurotrauma, 30, pp.897~906 (2013)
  47. Martí I Líndez AA, "Arginine-dependent immune responses", Cell Mol Life Sci, 78, pp.5303~5324 (2021)
  48. Bower RH, "Early enteral administration of a formula(Impact)supplemented with arginine, nucleotides, and fish oil in intensive care unit patients : results of a multicenter, prospective, randomized, clinical trial", Crit Care Med, 23, pp.436~449 (1995)
  49. Jeter CB, "Human mild traumatic brain injury decreases circulating branched-chain amino acids and their metabolite levels", J Neurotrauma, 30, pp.671~679 (2013)
  50. Elkind JA, "Efficacy, dosage, and duration of action of branched chain amino Acid therapy for traumatic brain injury", Front Neurol, 6, pp.73~ (2015)
  51. YudkoffM, "Interactions in the metabolism of glutamate and the branched-chain amino acids and ketoacids in the CNS", Neurochem Res, 42, pp.10~18 (2017)
  52. Drummond MJ, "Leucine-enriched nutrients and the regulation of mammalian target of rapamycin signalling and human skeletal muscle protein synthesis", Curr Opin Clin Nutr Metab Care, 11, pp.222~226 (2008)
  53. Aquilani R, "Branched-chain amino acids enhance the cognitive recovery of patients with severe traumatic brain injury", Arch Phys Med Rehabil, 86, pp.1729~1735 (2005)
  54. Sharma B, "Branched chain amino acids(BCAAs)and traumatic brain injury : a systematic review", J Head Trauma Rehabil, 33, pp.33~45 (2018)
  55. Hermanides J, "Glycaemic control targets after traumatic brain injury : a systematic review and meta-analysis", Crit Care, 22, pp.11~ (2018)
  56. Vespa P, "Tight glycemic control increases metabolic distress in traumatic brain injury : a randomized controlled withinsubjects trial", Crit Care Med, 40, pp.1923~1929 (2012)
  57. Oddo M, "Impact of tight glycemic control on cerebral glucose metabolism after severe brain injury : a microdialysis study", Crit Care Med, 36, pp.3233~3238 (2008)
  58. NICE-SUGAR Study Investigators for the Australian, "Intensive versus conventional glucose control in critically ill patients with traumatic brain injury : long-term follow-up of a subgroup of patients from the NICE-SUGAR study", Intensive Care Med, 41, pp.1037~1047 (2015)
  59. Rai VR, "Effects of immunonutrition on biomarkers in traumatic brain injury patients in Malaysia : a prospective randomized controlled trial", BMC Anesthesiol, 17, pp.81~ (2017)
  60. Young B, "Zinc supplementation is associated with improved neurologic recovery rate and visceral protein levels of patients with severe closed head injury", J Neurotrauma, 13, pp.25~34 (1996)
  61. Lee JM, "The effect of vitamin D supplementation in patients with acute traumatic brain injury", World Neurosurg, 126, pp.e1421~e1426 (2019)
  62. Razmkon A, "Administration of vitamin C and vitamin E in severe head injury : a randomized double-blind controlled trial", Clin Neurosurg, 58, pp.133~137 (2011)
  63. Gardner RC, "Geriatric traumatic brain injury : epidemiology, outcomes, knowledge gaps, and future directions", J Neurotrauma, 35, pp.889~906 (2018)
  64. Su WT, "Geriatric Nutritional Risk Index as a prognostic factor for mortality in elderly patients with moderate to severe traumatic brain injuries", Risk Manag Healthc Policy, 14, pp.2465~2474 (2021)
  65. Gavazzi G, "Ageing and infection", Lancet Infect Dis, 2, pp.659~666 (2002)

관련 논문AI추천

이 간행물의 다른 논문 (10건)