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일부 농촌지역주민의 High Sensitivity C-Reactive Protein(hsCRP)과 고혈압의 관련성

The Association of High Sensitivity C-Reactive Protein(hsCRP) with Hypertension in Some Rural Residents

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Abstract

Objectives : This study was performed to assess the association between high sensitivity C-Reactive Protein (hsCRP) and hypertension. Methods : We evaluated the relationship between hsCRP with hypertension and other cardiovascular risk factors, using a cross-sectional survey of 202 people over the age of 50, living in a rural area. A logistic regression analysis was used to study the association between hsCRP and hypertension. The hsCRP levels were divided in quartiles, and the odds ratios (OR), with 95% confidence intervals (95% CI), calculated, using the lowest quartile as a reference. Results : The subjects consisted of 37.1% men and 62.9% women, with a mean (SD) hsCRP level of 1.9(±3.0) ㎎/ℓ. The overall prevalence of hypertension was 61.4%. The prevalence of hypertension according to the hsCRP quartile was not statistically significant. After adjustment for confounding variables, the prevalence of hypertension according to the subjects in the 2nd, 3rd and 4th hsCRP quartiles were 1.418 (95% CI=0.554-3.628), 1.124 (95% CI=0.392-3.214) and 0.892 (95% CI=0.312-2.547) times higher, respectively, compared to those in the 1st quartile. Conclusions : The results showed that the level of hsCRP was not a risk factor for hypertension among adults aged over 50 years, living in a rural area. A further study should be performed to find the association between hsCRP and hypertension.

참고문헌 (26)

  1. Burt VL, "Prevalence of hypertension in the US adultpopulation results from the third NationalHealth and Nutrition Examination Survey", 25, pp.305~313 (1988)
  2. Xu X, "Environmental and occupationaldeterminants of blood pressure in ruralcommunities in China", 7, pp.95~106 (1997)
  3. 보건복지부, "한국인의 주요 상병 및 건강행태 분석 - 2001년 국민건강 영양조사 건강부분 심층분석 결과 -" (2003)
  4. Jee SH, "Smoking andatherosclerotic cardiovascular disease in menwith low levels of serum cholesterol:The koreanmedical insurance corporation study", 282, pp.2149~2155 (1999)
  5. Fuentes RM, "Familial aggregation ofblood pressure:a population-based family studyin eastern Finland", 14, pp.441~445 (2000)
  6. MacMahon S, "Obesity and hypertension:Epidemiological andclinical issues", suppl b, pp.57~70 (1987)
  7. Elliott P, "Observational studies of salt and bloodpressure", 17, pp.~18 (1991)
  8. Marmot MG, "Alcohol and bloodpressure:The intersalt study", 308, pp.1263~1267 (1994)
  9. Staessen JA, "Life style as adeterminant of blood pressure in the generalpopulation", 7, pp.685~694 (1994)
  10. Stamler J, "Relationship to blood pressure ofcombinations of dietary macronutrients Findings of the multiple risk factor interventiontrial", 94, pp.2417~2423
  11. Sung KC, "High sensitivityC-reactive protein as an independentrisk factorfor essential hypertension", 16, pp.429~433 (2003)
  12. Ross R, "Atherosclerosis:An inflammatorydisease", 340, pp.115~126 (1999)
  13. Pfeffer M, "Elevation of tumor necrosis factor-αandincreased risk of recurrent coronary events aftermyocardial infarction", 101, pp.2149~2153
  14. Sinisalo J, "Relation of inflammation to vascularfunction in patients with coronary heart disease", 149, pp.403~411 (2000)
  15. Bautista LE, "Is Creactiveprotein an independent risk factor foressential hypertension", 19, pp.857~861
  16. Black HR, "Seventh report of the joint national committeeon the prevention evaluation andtreatment of high blood pressure", 42, pp.1206~1252, and the National High Blood PressureEducation Program Coordinating Committee
  17. Friedewald WT, "Estimation of the concentration of low-densitylipoprotein cholesterol in plasma,without theuse of the preparative ultracentrifuge", 19, pp.499~502
  18. Heeschen C, "Predictive value of C-reactive protein andtroponin T in patients with unstable angina:acomparative analysis", 35, pp.1535~1542 (2000)
  19. Mendall MA, "C-reactive protein and itsrelation to cardiovascular risk factors:apopulation based cross sectional study", 312, pp.1061~1065 (1996)
  20. de Ferranti S, "C-reactive protein andcardiovascualr disease:a review of riskprediction and interventions", 317, pp.1~15 (2002), Clinica ChimicaActa
  21. Fichtlscherer S, "Elevated Creactiveprotein levels and impaired endothelialvasoreactivity in patients with coronary arterydisease", 102, pp.1000~1006 (2000)
  22. Fernandeez-Real JM, "Circulating interleukin 6 levels,blood pressure,and insulin sensitivity in apparently healthymen and women", 86, pp.1154~1159
  23. Rohde LE, "Surveyof C-reactive protein and cardiovascularriskfactors in apparently healthy men", 84, pp.1018~1022 (1999)
  24. Ko UY, "Prevalence and epidemiologic characteristics ofhypertension in a rural adult population", 18, pp.55~63
  25. Kin HO, "A study on the prevalence rate ofhypertension and the actual conditions ofcontrol", 10, pp.154~172
  26. Oh BH, "Korean Association of Public Health Doctor The prevalence of hypertensionin the rural area of Korea", 53, pp.299~315

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