공복혈당과 당화혈색소에 의한 당뇨병 진단 비교
A Comparison of Fasting Glucose and HbA1c for the Diagnosis of Diabetes Mellitus Among Korean Adults
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Objectives: The American Diabetes Association (ADA) has recently recommended the HbA1c assay as one of four options for making the diagnosis of diabetes mellitus, with a cut-point of ≥6.5%. We compared the HbA1c assay and the fasting plasma glucose level for making the diagnosis of diabetes among Korean adults. Methods: We analyzed 8710 adults (age 45-74 years), who were not diagnosed as having diabetes mellitus, from the Namwon study population. A fasting plasma glucose level of ≥126 mg/dL and an A1c of ≥6.5% were used for the diagnosis of diabetes. The kappa index of agreement was calculated to measure the agreement between the diagnosis based on the fasting plasma glucose level and the HbA1c. Results: The kappa index of agreement between the fasting plasma glucose level and HbA1c was 0.50. Conclusions: The agreement between the fasting plasma glucose and HbA1c for the diagnosis of diabetes was moderate for Korean adults.
Abstract
Objectives: The American Diabetes Association (ADA) has recently recommended the HbA1c assay as one of four options for making the diagnosis of diabetes mellitus, with a cut-point of ≥6.5%. We compared the HbA1c assay and the fasting plasma glucose level for making the diagnosis of diabetes among Korean adults. Methods: We analyzed 8710 adults (age 45-74 years), who were not diagnosed as having diabetes mellitus, from the Namwon study population. A fasting plasma glucose level of ≥126 mg/dL and an A1c of ≥6.5% were used for the diagnosis of diabetes. The kappa index of agreement was calculated to measure the agreement between the diagnosis based on the fasting plasma glucose level and the HbA1c. Results: The kappa index of agreement between the fasting plasma glucose level and HbA1c was 0.50. Conclusions: The agreement between the fasting plasma glucose and HbA1c for the diagnosis of diabetes was moderate for Korean adults.
참고문헌 (19)
- American Diabetes Association, "Screening for type 2 diabetes", Diabetes Care, 27(1), pp.S11~S14 (2004)
- "Report of the expert committee on the diagnosis and classification of diabetes mellitus", Diabetes Care, 20(7), pp.1183~1197 (1997)
- Gimeno SG, "Comparison of glucose tolerance categories according to World Health Organization and American Diabetes Association diagnostic criteria in a population-based study in Brazil. The Japanese- Brazilian Diabetes Study Group", Diabetes Care, 21(11), pp.1889~1892 (1998)
- Ko GT, "Use of the 1997 American Diabetes Association diagnostic criteria for diabetes in a Hong Kong Chinese population", Diabetes Care, 21(12), pp.2094~2097 (1998)
- Perry RC, "Early Diabetes Intervention Program (EDIP). HbA1c measurement improves the detection of type 2 diabetes in high-risk individuals with nondiagnostic levels of fasting plasma glucose: the Early Diabetes Intervention Program (EDIP)", Diabetes Care, 24(3), pp.465~471 (2001)
- Nichols GA, "Normal fasting plasma glucose and risk of type 2 diabetes diagnosis", Am J Med, 121(6), pp.519~524 (2008)
- Tirosh A, "Normal fasting plasma glucose levels and type 2 diabetes in young men", N Engl J Med, 353(14), pp.1454~1462 (2005)
- Gambino R, "Acidification of blood is superior to sodium fluoride alone as an inhibitor of glycolysis", Clin Chem, 55(5), pp.1019~1021 (2009)
- Bruns DE, "Stabilization of glucose in blood samples: why it matters", Clin Chem, 55(5), pp.850~852 (2009)
- Nathan DM, "The clinical information value of the glycosylated hemoglobin assay", N Engl J Med, 310(6), pp.341~346 (1984)
- Goldstein DE, "Is glycosylated hemoglobin clinically useful?", N Engl J Med, 310(6), pp.384~385 (1984)
- Kilpatrick ES, "Glycated haemoglobin values: problems in assessing blood glucose control in diabetes mellitus", BMJ, 309(6960), pp.983~986 (1994)
- Weykamp C, "The IFCC Reference Measurement System for HbA1c: a 6-year progress report", Clin Chem, 54(2), pp.240~248 (2008)
- Hoelzel W, "IFCC reference system for measurement of hemoglobin A1c in human blood and the national standardization schemes in the United States, Japan, and Sweden: a method-comparison study", Clin Chem, 50(1), pp.166~174 (2004)
- Little RR, "Effects of sample storage conditions on glycated hemoglobin measurement: evaluation of five different high performance liquid chromatography methods", Diabetes Technol Ther, 9(1), pp.36~42 (2007)
- Tapp RJ, "Longitudinal association of glucose metabolism with retinopathy: results from the Australian Diabetes Obesity and Lifestyle (AusDiab) study", Diabetes Care, 31(7), pp.1349~1354 (2008)
- Gillett MJ, "International Expert Committee report on the role of the A1c assay in the diagnosis of diabetes", Diabetes Care, 32(7), pp.1327~1334 (2009)
- American Diabetes Association, "Diagnosis and classification of diabetes mellitus", Diabetes Care, 33(1), pp.S62~S69 (2010)
- Carson AP, "Comparison of A1c and fasting glucose criteria to diagnose diabetes among U.S. adults", Diabetes Care, 33(1), pp.95~97 (2010)
