Evaluation of cephalometric characteristics and skeletal maturation of the cervical vertebrae and hand-wrist in girls with central precocious puberty
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Objective: This study aimed to evaluate the differences in cephalometric characteristics and skeletal maturation in girls with central precocious puberty (CPP) via lateral and hand-wrist radiographs. We also aimed to identify the indicators that are most effective for determining skeletal maturity in these patients. Methods: The study included 70 Korean girls (mean age, 8.5 ± 0.5 years) diagnosed with CPP at the Department of Pediatrics, and 48 normal healthy age-matched girls who visited the Department of Orthodontics and had no history of hormone treatment or growth problems. Skeletal maturation was evaluated using lateral cephalometric and hand-wrist radiographs using cervical vertebrae maturation indicators (CVMI) and skeletal maturity indicators (SMI). Results: The mean mandibular plane angle was smaller in the CPP group than in the control group (35.8o ± 4.9o vs. 39.0o ± 6.5o), resulting in greater posterior facial height (p = 0.003). SMI was significantly greater in the CPP group (3.5 ± 1.4 vs. 2.0 ± 1.0) than in the control group (p = 0.001) and was significantly associated with CPP (r = 0.492; p = 0.001), whereas CVMI was not. Conclusions: In comparison with the control group, the CPP group exhibited a smaller mandibular plane angle, greater posterior facial height, and greater skeletal maturation. SMI may be more suitable than CVMI for determining skeletal maturation in CPP. Hand-wrist radiography is recommended in addition to lateral cephalogram for predicting growth in girls with CPP.
Abstract
Objective: This study aimed to evaluate the differences in cephalometric characteristics and skeletal maturation in girls with central precocious puberty (CPP) via lateral and hand-wrist radiographs. We also aimed to identify the indicators that are most effective for determining skeletal maturity in these patients. Methods: The study included 70 Korean girls (mean age, 8.5 ± 0.5 years) diagnosed with CPP at the Department of Pediatrics, and 48 normal healthy age-matched girls who visited the Department of Orthodontics and had no history of hormone treatment or growth problems. Skeletal maturation was evaluated using lateral cephalometric and hand-wrist radiographs using cervical vertebrae maturation indicators (CVMI) and skeletal maturity indicators (SMI). Results: The mean mandibular plane angle was smaller in the CPP group than in the control group (35.8o ± 4.9o vs. 39.0o ± 6.5o), resulting in greater posterior facial height (p = 0.003). SMI was significantly greater in the CPP group (3.5 ± 1.4 vs. 2.0 ± 1.0) than in the control group (p = 0.001) and was significantly associated with CPP (r = 0.492; p = 0.001), whereas CVMI was not. Conclusions: In comparison with the control group, the CPP group exhibited a smaller mandibular plane angle, greater posterior facial height, and greater skeletal maturation. SMI may be more suitable than CVMI for determining skeletal maturation in CPP. Hand-wrist radiography is recommended in addition to lateral cephalogram for predicting growth in girls with CPP.
참고문헌 (22)
- Bishara SE, "Facial and dental changes in adolescents and their clinical implications", Angle Orthod, 70, pp.471~483 (2000)
- Petrovic A, "Craniofacial growth theory and orthodontic treatment. Craniofacial growth series", pp.13~73 (1990), University of Michigan, Center for Human Growth and Development
- Malmgren O, "Treatment with an orthopedic appliance system in relation to treatment intensity and growth periods. A study of initial effects", Am J Orthod Dentofacial Orthop, 91, pp.143~151 (1987)
- Björk A, "Prediction of the age of maximum puberal growth in body height", Angle Orthod, 37, pp.134~143 (1967)
- Parent AS, "The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration", Endocr Rev, 24, pp.668~693 (2003)
- Mul D, "The use of GnRH agonists in precocious puberty", Eur J Endocrinol, 159(Suppl 1), pp.S3~S8 (2008)
- Lee HK, "Evaluation of characteristics of the craniofacial complex and dental maturity in girls with central precocious puberty", Angle Orthod, 88, pp.582~589 (2018)
- Hassel B, "Skeletal maturation evaluation using cervical vertebrae", Am J Orthod Dentofacial Orthop, 107, pp.58~66 (1995)
- Fishman LS, "Radiographic evaluation of skeletal maturation. A clinically oriented method based on hand-wrist films", Angle Orthod, 52, pp.88~112 (1982)
- Al Khal HA, "Elimination of hand-wrist radiographs for maturity assessment in children needing orthodontic therapy", Skeletal Radiol, 37, pp.195~200 (2008)
- Szemraj A, "Is the cervical vertebral maturation (CVM)method effective enough to replace the hand-wrist maturation (HWM) method in determining skeletal maturation?-A systematic review", Eur J Radiol, 102, pp.125~128 (2018)
- Terçarolli SP, "Skeletal and vertebral age-a literature review", Ortop Rev Int Func, 1, pp.400~411 (2005)
- Tanner JM, "Atlas of children's growth, normal variation and growth disorders", J Pediatr Orthop, 3, pp.531~ (1983)
- Choi SH, "Effect of growth hormone treatment on craniofacial growth in children: idiopathic short stature versus growth hormone deficiency", J Formos Med Assoc, 116, pp.313~321 (2017)
- Hinkle DE, "Applied statistics for the behavioral sciences" (2003), Houghton Mifflin College Division
- Health Insurance Review & Assessment Service (KR), "Four-character subcategories statistics", Health Insurance Review & Assessment Service, ~ (2019)
- 백지선, "Predictive Value of Dental Maturity for a Positive Gonadotropin-Releasing Hormone Stimulation Test Result in Girls with Precocious Puberty", Journal of Korean Medical Science, 32(2), pp.296~302 (2017), 대한의학회
- Hoseini M, "Comparative evaluation of the efficacy of hand-wrist and cervical vertebrae radiography for the determination of skeletal age", Iran J Radiol, 13, pp.e21695~ (2016)
- Ye-Seul Lee, "Evaluation of skeletal maturity in the cervical vertebrae and hand-wrist in relation to vertical facial types", 대한치과교정학회지, 49(5), pp.319~325 (2019), 대한치과교정학회[DOI]
- Warmeling D, "Comparative study of two skeletal maturation evaluation indexes", Rev Odonto Ciênc, 25, pp.188~193 (2010)
- Flores-Mir C, "Use of skeletal maturation based on hand-wrist radiographic analysis as a predictor of facial growth : a systematic review", Angle Orthod, 74, pp.118~124 (2004)
- Jabour ASA, "Assessment of spheno-occipital synchondrosis fusion timing and an evaluation of its relationship with skeletal maturity, dental maturity and mandibular growth", PhD, pp.2017