Health-related Quality of Life of Patients With Diabetes Mellitus Measured With the Bahasa Indonesia Version of EQ-5D in Primary Care Settings in Indonesia
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Objectives: Diabetes mellitus (DM) is a serious public health issue that places a heavy financial, social, and health-related burden on individuals, families, and healthcare systems. Self-reported health-related quality of life (HRQoL) is extensively used for monitoring the general population’s health conditions and measuring the effectiveness of interventions. Therefore, this study investigated HRQoL and associated factors among patients with type 2 DM at a primary healthcare center in Indonesia.Methods: A cross-sectional study was conducted in Klaten District, Central Java, Indonesia, from May 2019 to July 2019. In total, 260 patients with DM registered with National Health Insurance were interviewed. HRQoL was measured with the EuroQol Group’s validated Bahasa Indonesia version of the EuroQoL 5-Dimension 5-Level (EQ-5D-5L) with the Indonesian value set. Multivariate regression models were used to identify factors influencing HRQoL.Results: Data from 24 patients were excluded due to incomplete information. Most participants were men (60.6%), were aged above 50 years (91.5%), had less than a senior high school education (75.0%), and were unemployed (85.6%). The most frequent health problems were reported for the pain/discomfort dimension (64.0%) followed by anxiety (28.4%), mobility (17.8%), usual activities (10.6%), and self-care (6.8%). The average EuroQoL 5-Dimension (EQ-5D) index score was 0.86 (95% confidence interval [CI], 0.83 to 0.88). In the multivariate ordinal regression model, a higher education level (coefficient, 0.08; 95% CI, 0.02 to 0.14) was a significant predictor of the EQ-5D-5L utility score.Conclusions: Patients with diabetes had poorer EQ-5D-5L utility values than the general population. DM patients experienced pain/discomfort and anxiety. There was a substantial positive relationship between education level and HRQoL.
Abstract
Objectives: Diabetes mellitus (DM) is a serious public health issue that places a heavy financial, social, and health-related burden on individuals, families, and healthcare systems. Self-reported health-related quality of life (HRQoL) is extensively used for monitoring the general population’s health conditions and measuring the effectiveness of interventions. Therefore, this study investigated HRQoL and associated factors among patients with type 2 DM at a primary healthcare center in Indonesia.Methods: A cross-sectional study was conducted in Klaten District, Central Java, Indonesia, from May 2019 to July 2019. In total, 260 patients with DM registered with National Health Insurance were interviewed. HRQoL was measured with the EuroQol Group’s validated Bahasa Indonesia version of the EuroQoL 5-Dimension 5-Level (EQ-5D-5L) with the Indonesian value set. Multivariate regression models were used to identify factors influencing HRQoL.Results: Data from 24 patients were excluded due to incomplete information. Most participants were men (60.6%), were aged above 50 years (91.5%), had less than a senior high school education (75.0%), and were unemployed (85.6%). The most frequent health problems were reported for the pain/discomfort dimension (64.0%) followed by anxiety (28.4%), mobility (17.8%), usual activities (10.6%), and self-care (6.8%). The average EuroQoL 5-Dimension (EQ-5D) index score was 0.86 (95% confidence interval [CI], 0.83 to 0.88). In the multivariate ordinal regression model, a higher education level (coefficient, 0.08; 95% CI, 0.02 to 0.14) was a significant predictor of the EQ-5D-5L utility score.Conclusions: Patients with diabetes had poorer EQ-5D-5L utility values than the general population. DM patients experienced pain/discomfort and anxiety. There was a substantial positive relationship between education level and HRQoL.
참고문헌 (37)
- Tran BX, "Determinants of health-related quality of life in adults living with HIV in Vietnam", AIDS Care, 23(10), pp.1236~1245 (2011)
- Kruk ME, "Assessing health system performance in developing countries : a review of the literature", Health Policy, 85(3), pp.263~276 (2008)
- Kularatna S, "EQ-5D-3L derived population norms for health related quality of life in Sri Lanka", PLoS One, 9(11), pp.e108434~ (2014)
- "Global action plan for the prevention and control of NCDs 2013-2020" (2013)[URL]
- "IDF diabetes atlas eighth edition 2017"[URL]
- "In the year 2030, the prevalence of diabetes mellitus in Indonesia reaches 21.3 million people" (2009)[URL]
- Prajapati VB, "Assessment of quality of life in type II diabetic patients using the modified diabetes quality of life(MDQoL)-17 questionnaire", Braz J Pharm Sci, 53(4), pp.e17144~ (2017)
- UK Prospective Diabetes Study Group, "Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes : UKPDS 38", BMJ, 317(7160), pp.703~713 (1998)
- Gold MR, "Measure-dependent variation in burden of disease estimates : implications for policy", Med Care, 40(3), pp.260~266 (2002)
- Jing X, "Related factors of quality of life of type 2 diabetes patients : a systematic review and meta-analysis", Health Qual Life Outcomes, 16(1), pp.189~ (2018)
- Rabin R, "From translation to version management : a history and review of methods for the cultural adaptation of the EuroQol five-dimensional questionnaire", Value Health, 17(1), pp.70~76 (2014)
- Herdman M, "Development and preliminary testing of the new five-level version of EQ-5D(EQ-5D-5L)", Qual Life Res, 20(10), pp.1727~1736 (2011)
- Perwitasari DA, "Relationship of therapeutic outcome with quality of life on type 2 diabetes mellitus patients in Abdul Azis Singkawang hospital", IOP Conf Ser Mater Sci Eng, 259, pp.012023~ (2017)
- Arifin B, "Health-related quality of life in Indonesian type 2 diabetes mellitus outpatients measured with the Bahasa version of EQ-5D", Qual Life Res, 28(5), pp.1179~1190 (2019)
- Flatz A, "Association between education and quality of diabetes care in Switzerland", Int J Gen Med, 8, pp.87~92 (2015)
- Coffey JT, "Valuing health-related quality of life in diabetes", Diabetes Care, 25(12), pp.2238~2243 (2002)
- Redekop WK, "Health-related quality of life and treatment satisfaction in Dutch patients with type 2 diabetes", Diabetes Care, 25(3), pp.458~463 (2002)
- Lung TW, "A meta-analysis of health state valuations for people with diabetes : explaining the variation across methods and implications for economic evaluation", Qual Life Res, 20(10), pp.1669~1678 (2011)
- Drummond MF, "Methods for the economic evaluation of health care programmes", pp.9~ (2015), Oxford University Press
- Trikkalinou A, "Type 2 diabetes and quality of life", World J Diabetes, 8(4), pp.120~129 (2017)
- "Measuring healthy days: population assessment of health-related quality of life" (2000)[URL]
- Ruževičius J, "Quality of life and of working life: conceptions and research", 17th Toulon-Verona International Conference, pp.317~334 (2014), John Moores University
- Edgerton JD, "Handbook of social indicators and quality of life research", pp.265~296 (2012), Springer
- Sakamaki H, "Measurement of HRQL using EQ-5D in patients with type 2 diabetes mellitus in Japan", Value Health, 9(1), pp.47~53 (2006)
- 이우제, "Health-Related Quality of Life Using the EuroQol 5D Questionnaire in Korean Patients with Type 2 Diabetes", Journal of Korean Medical Science, 27(3), pp.255~260 (2012), 대한의학회
- Mehring M, "Disease management programs for patients with type 2 diabetes mellitus in Germany : a longitudinal population-based descriptive study", Diabetol Metab Syndr, 9, pp.37~ (2017)
- "Prolanis (Chronic Disease Management Program) practical guide" (2014)[URL]
- "Determining sample size" (2012)[URL]
- Purba FD, "The Indonesian EQ-5D-5L value set", Pharmacoeconomics, 35(11), pp.1153~1165 (2017)
- Saleh F, "Assessment of health-related quality of life of Bangladeshi patients with type 2 diabetes using the EQ-5D : a cross-sectional study", BMC Res Notes, 8, pp.497~ (2015)
- Ahmad M, "Prolanis implementation effective to control fasting blood sugar, HBA1C and total cholesterol levels in patients with type 2 diabetes", J Ners, 12(1), pp.88~98 (2017)
- Raraswati A, "Role of Prolanis program in decreasing fasting blood glucose on type 2 diabetic patient in Puskesmas Kecamatan Jatinangor", J Health Syst, 4(2), pp.65~70 (2018)
- Worach-Kardas H, "Quality of life and health state of long-term unemployed in older production age", Appl Res Qual Life, 9(2), pp.335~353 (2014)
- American Association of Diabetes Educators, "An effective model of diabetes care and education : revising the aade7 self-care behaviors®", Diabetes Educ, 46(2), pp.139~160 (2020)
- Sendekie AK, "Health-related quality of life and its determinants among patients with diabetes mellitus : a multicentre cross-sectional study in Northwest Ethiopia", BMJ Open, 13(1), pp.e068518~ (2023)
- Sparring V, "Diabetes duration and health-related quality of life in individuals with onset of diabetes in the age group 15-34 years-a Swedish population-based study using EQ-5D", BMC Public Health, 13, pp.377~ (2013)
- Devlin NJ, "Valuing health-related quality of life : an EQ-5D-5L value set for England", Health Econ, 27(1), pp.7~22 (2018)