피부진균증에서 조직검사와 화학염색
Histopathology and Histochemistry in Cutaneous Fungal Infections
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Dermatomycosis refers to any fungal infection of the skin and may be caused by dermatophytes, yeast, or other fungi, including those that do not usually cause cutaneous disease. Clinical diagnosis of a dermatomycosis can be confirmed by microscopic detection of fungal elements, by identification of the species through culture, or by histologic evidence of the presence of fungal material in the tissue. In superficial mycoses, direct smear with KOH and fungal culture are the most valuable and useful diagnostic methods. For this reason, skin biopsy is not often employed in the workup of dermatophytosis or other superficial mycoses. But it is useful in diagnosis of deep fungal infections and some lesions in which KOH examination of scale is negative. This review article aims to provide insights on the histopathology and various special stains in diagnosing dermatomycosis.
Abstract
Dermatomycosis refers to any fungal infection of the skin and may be caused by dermatophytes, yeast, or other fungi, including those that do not usually cause cutaneous disease. Clinical diagnosis of a dermatomycosis can be confirmed by microscopic detection of fungal elements, by identification of the species through culture, or by histologic evidence of the presence of fungal material in the tissue. In superficial mycoses, direct smear with KOH and fungal culture are the most valuable and useful diagnostic methods. For this reason, skin biopsy is not often employed in the workup of dermatophytosis or other superficial mycoses. But it is useful in diagnosis of deep fungal infections and some lesions in which KOH examination of scale is negative. This review article aims to provide insights on the histopathology and various special stains in diagnosing dermatomycosis.
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