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Candida albicans 에 의한 칸디다 안구내염에 병발한 감염성 흉부 대동맥류 1예

Infected Thoracic Aortic Aneurysm Concurrent with Endophthalmitis by Candida albicans: a Case Report

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Candida species cause various invasive fungal diseases, including candidemia, endocarditis, endophthalmitis, peritonitis, osteomyelitis and arthritis, but infected (mycotic) aortic aneurysms caused by Candida species are very rare. So, we report a case of infected thoracic aortic aneurysm concurrent with endophthalmitis by Candida albicans in a 42-year-old man. The patient initially was diagnosed with candidial endophthalmitis and hospitalized for vitrectomy. On admission, he had chest CT taken and infected thoracic aortic aneurysm was detected. He treated with antifungal agent and resection and patch repair of aortic aneurysm. Two months later, a new aneurysm on the patch repair site was detected and thoracic endovascular aortic repair (TEVAR) was performed. After TEVAR and long-term antifungal therapy, his infected aortic aneurysm has been successfully treated.

Abstract

Candida species cause various invasive fungal diseases, including candidemia, endocarditis, endophthalmitis, peritonitis, osteomyelitis and arthritis, but infected (mycotic) aortic aneurysms caused by Candida species are very rare. So, we report a case of infected thoracic aortic aneurysm concurrent with endophthalmitis by Candida albicans in a 42-year-old man. The patient initially was diagnosed with candidial endophthalmitis and hospitalized for vitrectomy. On admission, he had chest CT taken and infected thoracic aortic aneurysm was detected. He treated with antifungal agent and resection and patch repair of aortic aneurysm. Two months later, a new aneurysm on the patch repair site was detected and thoracic endovascular aortic repair (TEVAR) was performed. After TEVAR and long-term antifungal therapy, his infected aortic aneurysm has been successfully treated.

참고문헌 (7)

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  5. Arendrup MC, "Multidrug-resistant candida:epidemiology, molecular mechanisms, and treatment", J Infect Dis, 216(suppl_3), pp.S445~S451 (2017)
  6. Ikeda M, "Contained rupture of infected abdominal aortic aneurysm due to systemic candidiasis", Cardiovasc Surg, 3, pp.711~714 (1995)
  7. Barry MC, "Candida albicans mycotic abdominal aortic aneurysm", Eur J Vasc Endovasc Surg, 13, pp.237~239 (1997)

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