Severe Skin and Soft Tissue Infection of Patients Admitted to Intensive Care Units
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Skin and soft tissue infections (SSTIs) can occasionally progress to life-threatening conditions, such as septic shock, requiring intensive care unit admission. Their risk factors include diabetes mellitus, chronic renal failure, chronic vascular disease, malignancy, and acquired immune deficiency syndrome. However, early diagnosis is challenging due to initially benign skin lesions and the absence of systemic symptoms such as fever. This review focuses on severe bacterial infections such as necrotizing fasciitis, gas gangrene, and toxic shock syndrome, examining their etiology and management. These severe SSTIs should be understood for the early diagnosis, appropriate treatment, and improved patient outcomes. Dermatologists play a vital role in recognizing and managing these infections.
Abstract
Skin and soft tissue infections (SSTIs) can occasionally progress to life-threatening conditions, such as septic shock, requiring intensive care unit admission. Their risk factors include diabetes mellitus, chronic renal failure, chronic vascular disease, malignancy, and acquired immune deficiency syndrome. However, early diagnosis is challenging due to initially benign skin lesions and the absence of systemic symptoms such as fever. This review focuses on severe bacterial infections such as necrotizing fasciitis, gas gangrene, and toxic shock syndrome, examining their etiology and management. These severe SSTIs should be understood for the early diagnosis, appropriate treatment, and improved patient outcomes. Dermatologists play a vital role in recognizing and managing these infections.
참고문헌 (28)
- Vincent JL, "EPIC II Group of Investigators. International study of the prevalence and outcomes of infection in intensive care units", JAMA, 302, pp.2323~2329 (2009)
- Engel C, "Epidemiology of sepsis in Germany : results from a national prospective multicenter study", Intensive Care Med, 33, pp.606~618 (2007)
- Llopis F, "Review of 1. 250 episodes of skin and soft tissue infections attended at 49 hospital emergency departments", Rev Esp Quimioter, 27, pp.115~121 (2014)
- Peetermans M, "Necrotizing skin and soft-tissue infections in the intensive care unit", Clin Microbiol Infect, 26, pp.8~17 (2020)
- Vinh DC, "Rapidly progressive soft tissue infections", Lancet Infect Dis, 5, pp.501~513 (2005)
- Marques SA, "Severe bacterial skin infections", An Bras Dermatol, 95, pp.407~417 (2020)
- Stevens DL, "Necrotizing soft-tissue infections", N Engl J Med, 377, pp.2253~2265 (2017)
- Adams EM, "Streptococcal myositis", Arch Intern Med, 145, pp.1020~1023 (1985)
- Kuehl R, "High mortality of non-Fournier necrotizing fasciitis with Enterobacteriales : time to rethink classification?", Clin Infect Dis, 69, pp.147~150 (2019)
- Jabbour G, "Pattern and predictors of mortality in necrotizing fasciitis patients in a single tertiary hospital", World J Emerg Surg, 11, pp.40~ (2016)
- Nordqvist G, "Ten years of treating necrotizing fasciitis", Infect Dis(Lond), 47, pp.319~325 (2015)
- van Stigt SF, "Review of 58 patients with necrotizing fasciitis in the Netherlands", World J Emerg Surg, 11, pp.21~ (2016)
- Kulasegaran S, "Necrotizing fasciitis : 11-year retrospective case review in South Auckland", ANZ J Surg, 86, pp.826~830 (2016)
- Wong CH, "Necrotizing fasciitis : clinical presentation, microbiology, and determinants of mortality", J Bone Joint Surg Am, 85, pp.1454~1460 (2003)
- Dhanasekara CS, "Global patterns of necrotizing soft tissue infections : A systematic review and meta-analysis", Surgery, 170, pp.1718~1726 (2021)
- Hua C, "Necrotising soft-tissue infections", Lancet Infect Dis, 23, pp.e81~e94 (2023)
- Wong CH, "The LRINEC(Laboratory Risk Indicator for Necrotizing Fasciitis)score : a tool for distinguishing necrotizing fasciitis from other soft tissue infections", Crit Care Med, 32, pp.1535~1541 (2004)
- Stevens DL, "Practice guidelines for the diagnosis and management of skin and soft tissue infections : 2014 update by the Infectious Diseases Society of America", Clin Infect Dis, 59, pp.e10~e52 (2014)
- Leiblein M, "Clostridial gas gangrene-a rare but deadly infection : case series and comparison to other necrotizing soft tissue infections", Orthop Surg, 12, pp.1733~1747 (2020)
- Chapnick EK, "Necrotizing soft-tissue infections", Infect Dis Clin North Am, 10, pp.835~855 (1996)
- Gottlieb M, "The evaluation and management of toxic shock syndrome in the emergency department : a review of the literature", J Emerg Med, 54, pp.807~814 (2018)
- Lappin E, "Gram-positive toxic shock syndromes", Lancet Infect Dis, 9, pp.281~290 (2009)
- Matsushima A, "Low level of TSST-1 antibody in burn patients with toxic shock syndrome caused by methicillin-resistant Staphylococcus aureus", J Burn Care Res, 36, pp.e120~e124 (2015)
- Kotb M, "Association of human leukocyte antigen with outcomes of infectious diseases : the streptococcal experience", Scand J Infect Dis, 35, pp.665~669 (2003)
- Celie KB, "Toxic shock syndrome after surgery : case presentation and systematic review of the literature", Plast Reconstr Surg Glob Open, 8, pp.e2499~ (2020)
- Stevens D, "Streptococcal toxic shock syndrome", Clin Microbiol Infect, 8, pp.133~136 (2002)
- McCormick JK, "Toxic shock syndrome and bacterial superantigens : an update", Annu Rev Microbiol, 55, pp.77~104 (2001)
- Atchade E, "Toxic shock syndrome : a literature review", Antibiotics(Basel), 13, pp.96~ (2024)