본문 바로가기
KERD
논문KCI 등재

Prevalence of latent tuberculosis infection among tuberculosis laboratory workers in Iran

1

조회

0

다운로드

0

인용

0

참고문헌

키워드

초록

OBJECTIVES: The risk of transmission of Mycobacterium tuberculosis from patients to health care workers (HCWs) is a neglected problem in many countries, including Iran. The aim of this study was to estimate the prevalence of latent tuberculosis (TB) infection (LTBI) among TB laboratory staff in Iran, and to elucidate the risk factors associated with LTBI. METHODS: All TB laboratory staff (689 individuals) employed in the TB laboratories of 50 Iranian universities of medical sciences and a random sample consisting of 317 low-risk HCWs were included in this cross-sectional study. Participants with tuberculin skin test indurations of 10 mm or more were considered to have an LTBI. RESULTS: The prevalence of LTBI among TB laboratory staff and low-risk HCWs was 24.83% (95% confidence interval [CI], 21.31 to 27.74%) and 14.82% (95% CI, 11.31 to 19.20%), respectively. No active TB cases were found in either group. After adjusting for potential confounders, TB laboratory staff were more likely to have an LTBI than low-risk HCWs (prevalence odds ratio, 2.06; 95% CI, 1.35 to 3.17). CONCLUSIONS: This study showed that LTBI are an occupational health problem among TB laboratory staff in Iran. This study reinforces the need to design and implement simple, effective, and affordable TB infection control programs in TB laboratories in Iran.

Abstract

OBJECTIVES: The risk of transmission of Mycobacterium tuberculosis from patients to health care workers (HCWs) is a neglected problem in many countries, including Iran. The aim of this study was to estimate the prevalence of latent tuberculosis (TB) infection (LTBI) among TB laboratory staff in Iran, and to elucidate the risk factors associated with LTBI. METHODS: All TB laboratory staff (689 individuals) employed in the TB laboratories of 50 Iranian universities of medical sciences and a random sample consisting of 317 low-risk HCWs were included in this cross-sectional study. Participants with tuberculin skin test indurations of 10 mm or more were considered to have an LTBI. RESULTS: The prevalence of LTBI among TB laboratory staff and low-risk HCWs was 24.83% (95% confidence interval [CI], 21.31 to 27.74%) and 14.82% (95% CI, 11.31 to 19.20%), respectively. No active TB cases were found in either group. After adjusting for potential confounders, TB laboratory staff were more likely to have an LTBI than low-risk HCWs (prevalence odds ratio, 2.06; 95% CI, 1.35 to 3.17). CONCLUSIONS: This study showed that LTBI are an occupational health problem among TB laboratory staff in Iran. This study reinforces the need to design and implement simple, effective, and affordable TB infection control programs in TB laboratories in Iran.

참고문헌 (33)

  1. "Global tuberculosis control" (2010)[URL]
  2. Dye C, "Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project", JAMA, 282, pp.677~686 (1999)
  3. Field MJ, "Tuberculosis in the workplace", pp.14~ (2001), National Academy Press
  4. Cuhadaroglu C, "Increased risk of tuberculosis in health care workers: a retrospective survey at a teaching hospital in Istanbul, Turkey", BMC Infect Dis, 2, pp.14~ (2002)
  5. Baussano I, "Tuberculosis among health care workers", Emerg Infect Dis, 17, pp.488~494 (2011)
  6. Menzies D, "Meta-analysis: new tests for the diagnosis of latent tuberculosis infection: areas of uncertainty and recommendations for research", Ann Intern Med, 146, pp.340~354 (2007)
  7. Mathew A, "Risk factors for tuberculosis among health care workers in South India: a nested case-control study", J Clin Epidemiol, 66, pp.67~74 (2013)
  8. Rahbar M, "Prevalence and determinant of tuberculin skin test among health care workers of Imam Khomeini Hospital of Uremia, Iran", Shiraz E Med J, 8, pp.162~167 (2007)
  9. Besharat M, "Tuberculin skin test among 1,424 healthy employees in Chaharmahal province, Iran", Tanaffos, 10, pp.37~39 (2011)
  10. Talebi-Taher M, "Comparing the performance of QuantiFERON-TB Gold and Mantoux test in detecting latent tuberculosis infection among Iranian health care workers", Int J Occup Med Environ Health, 24, pp.359~366 (2011)
  11. Talebi TM, "Comparison of chest x-ray findings in health care workers with and without latent tuberculosis infection in Rasool Akram Hospital", J Sabzevar Univ Med Sci, 20, pp.505~510 (2014)
  12. Hashemi SH, "Prevalence of tuberculosis infection among health-care workers in Hamadan, west of Iran", Int J Infect Dis, 12, pp.e338~ (2008)
  13. National Collaborating Centre for Chronic Conditions, "Tuberculosis: clinical diagnosis and management of tuberculosis, and measures for its prevention and control", Royal College of Physicians, 43~54 (2006)
  14. Fennelly KP, "Health care workers and tuberculosis: the battle of a century", Int J Tuberc Lung Dis, 3, pp.363~364 (1999)
  15. Sepkowitz KA, "Tuberculin skin testing and the health care worker: lessons of the Prophit Survey", Tuber Lung Dis, 77, pp.81~85 (1996)
  16. Harries AD, "Practical and affordable measures for the protection of health care workers from tuberculosis in low-income countries", Bull World Health Organ, 75, pp.477~489 (1997)
  17. Jones-López EC, "Tuberculosis infection among HCWs", Int J Tuberc Lung Dis, 9, pp.591~ (2005)
  18. Whitehead M, "Equity and health sector reforms: can low-income countries escape the medical poverty trap?", Lancet, 358, pp.833~836 (2001)
  19. Joshi R, "Tuberculosis among health-care workers in low- and middle-income countries: a systematic review", PLoS Med, 3, pp.e494~ (2006)
  20. "Tuberculosis country profiles"[URL]
  21. Mostafavi E, "Comparison of the tuberculin skin test and the QuantiFERON-TB Gold test in detecting latent tuberculosis in health care workers in Iran", Epidemiol Health, 38, pp.e2016032~ (2016)
  22. Golchin M, "Tuberculin test in nursing and human-sciences students", J Res Med Sci, 10, pp.172~176 (2005)
  23. Doosti Irani A, "Lack of optimum practice among health care workers regarding tuberculosis in Iran: a knowledge, attitude, and practice study", Am J Infect Control, 43, pp.e7~e12 (2015)
  24. Kassim S, "Tuberculin skin testing to assess the occupational risk of Mycobacterium tuberculosis infection among health care workers in Abidjan, Côte d’Ivoire", Int J Tuberc Lung Dis, 4, pp.321~326 (2000)
  25. Keskiner R, "Risk of tuberculous infection among healthcare workers in a tertiary-care hospital in Ankara, Turkey", Infect Control Hosp Epidemiol, 25, pp.1067~1071 (2004)
  26. Yanai H, "Risk of Mycobacterium tuberculosis infection and disease among health care workers, Chiang Rai, Thailand", Int J Tuberc Lung Dis, 7, pp.36~45 (2003)
  27. Bonifacio N, "High risk for tuberculosis in hospital physicians, Peru", Emerg Infect Dis, 8, pp.747~748 (2002)
  28. Kayanja HK, "Tuberculosis infection among health care workers in Kampala, Uganda", Int J Tuberc Lung Dis, 9, pp.686~688 (2005)
  29. Roth VR, "A multicenter evaluation of tuberculin skin test positivity and conversion among health care workers in Brazilian hospitals", Int J Tuberc Lung Dis, 9, pp.1335~1342 (2005)
  30. Pai M, "Mycobacterium tuberculosis infection in health care workers in rural India: comparison of a whole-blood interferon gamma assay with tuberculin skin testing", JAMA, 293, pp.2746~2755 (2005)
  31. Cremers AL, "Assessing the consequences of stigma for tuberculosis patients in urban Zambia", PLoS One, 10, pp.e0119861~ (2015)
  32. Baghaei P, "Diabetes mellitus and tuberculosis facts and controversies", J Diabetes Metab Disord, 12, pp.58~ (2013)
  33. Pai M, "Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: an update", Ann Intern Med, 149, pp.177~184 (2008)

관련 논문AI추천

Comparison of the tuberculin skin test and the QuantiFERON-TB Gold test in detecting latent tuberculosis in health care workers in IranAbdolrazagh Hashemi-Shahraki, Amin Doosti-Irani, Ebrahim Ghaderi, Ehsan Mostafavi, Mahshid Nasehi, Saber Esmaeili, Saeed Sharafi한국역학회 · Epidemiology and Health2016 · 제38권 결핵전문 의료기관 근로자의 잠복결핵감염 요인김수남, 전경숙보건의료산업학회 · 보건의료산업학회지2024 · 제18권 제2호Comparing tuberculin skin test and interferon γ release assay (T-SPOT.TB) to diagnose latent tuberculosis infection in household contacts김세중, 박종선, 윤호일, 이연주, 이재호, 이춘택, 이현우, 조영재대한내과학회 · The Korean Journal of Internal Medicine2017 · 제32권 제3호일개 병원 내 의료종사자에서의 결핵 접촉자 조사김연재, 김태희, 배현주, 오성희, 장윤숙, 정선주대한소아감염학회 · Pediatric Infection and Vaccine2016 · 제23권 제2호A prospective cohort study of latent tuberculosis in adult close contacts of active pulmonary tuberculosis patients in Korea김호철, 김희진, 박선효, 이승준, 이종덕, 정이영, 조유지, Dick Menzies대한내과학회 · The Korean Journal of Internal Medicine2016 · 제31권 제3호Utility of QuantiFERON-TB In-Tube Test for Differentiating Active Tuberculosis from Latent Tuberculosis Infection in an Intermediate Burden Country최석훈, Bum Sik Chin, Chang Oh Kim, Han Sung Lee, Hee Kyung Choi, June Myung Kim, Jun Yong Choi, Myung Soo Kim, Sang Hoon Han, Su Jin Jeong, Young Goo Song대한감염학회 · Infection and Chemotherapy2008 · 제40권 제6호

이 간행물의 다른 논문 (61건)