Life expectancy of HIV-positive patients after diagnosis in Iran from 1986 to 2016: a retrospective cohort study at national and sub-national levels
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OBJECTIVES: Little is known about the life expectancy of individuals with human immunodeficiency virus (HIV) in Iran. This study therefore aimed to estimate the life expectancy of HIV-positive patients in Iran. METHODS: In this retrospective cohort study, we extracted data from the Center for Disease Control and Prevention of the Ministry of Health and Medical Education and the Death Registration System. We included patients aged 20 years and older who had a specified date of diagnosis. We estimated life expectancy and its 95% confidence intervals (CIs) using Chiang’s methodology. RESULTS: The overall life expectancy at the national level was 23.1 years (95% CI, 22.6 to 23.5). Life expectancy was 21.6 years (95% CI, 21.1 to 22.0) for men and 32.7 years (95% CI, 31.4 to 34.0) for women. The life expectancy of patients who did or did not receive antiretroviral therapy (ART) was 37.0 years (95% CI, 36.2 to 37.8) and 15.5 years (95% CI, 15.1 to 15.9), respectively. The life expectancy of patients with or without tuberculosis (TB) was 21.6 years (95% CI, 20.4 to 22.9) and 36.5 years (95% CI, 35.7 to 37.4), respectively. CONCLUSIONS: The life expectancy of Iranian HIV-positive patients was found to be very low. To improve their longevity, improvements in ART coverage and the control and treatment of TB are advised.
Abstract
OBJECTIVES: Little is known about the life expectancy of individuals with human immunodeficiency virus (HIV) in Iran. This study therefore aimed to estimate the life expectancy of HIV-positive patients in Iran. METHODS: In this retrospective cohort study, we extracted data from the Center for Disease Control and Prevention of the Ministry of Health and Medical Education and the Death Registration System. We included patients aged 20 years and older who had a specified date of diagnosis. We estimated life expectancy and its 95% confidence intervals (CIs) using Chiang’s methodology. RESULTS: The overall life expectancy at the national level was 23.1 years (95% CI, 22.6 to 23.5). Life expectancy was 21.6 years (95% CI, 21.1 to 22.0) for men and 32.7 years (95% CI, 31.4 to 34.0) for women. The life expectancy of patients who did or did not receive antiretroviral therapy (ART) was 37.0 years (95% CI, 36.2 to 37.8) and 15.5 years (95% CI, 15.1 to 15.9), respectively. The life expectancy of patients with or without tuberculosis (TB) was 21.6 years (95% CI, 20.4 to 22.9) and 36.5 years (95% CI, 35.7 to 37.4), respectively. CONCLUSIONS: The life expectancy of Iranian HIV-positive patients was found to be very low. To improve their longevity, improvements in ART coverage and the control and treatment of TB are advised.
참고문헌 (24)
- Massah O, "HIV programs in Iran (Persia), Iraq and Saudi Arabia: a brief review of current evidence in West and Southwest Asia", Addict Health, 8, pp.136~144 (2016)
- "HIV/AIDS" (2016)[URL]
- "Latest publications on epidemiological data"[URL]
- Jahanbakhsh F, "Prevalence of transmitted HIV drug resistance in Iran between 2010 and 2011", PLoS One, 8, pp.e61864~ (2013)
- "Islamic Republic of Iran AIDS progress report: on monitoring of the United Nations General Assembly special session on HIV and AIDS" (2015)[URL]
- "Final report of HIV/AIDS in Islamic Republic of Iran"[URL]
- Sabin CA, "Do people with HIV infection have a normal life expectancy in the era of combination antiretroviral therapy?", BMC Med, 11, pp.251~ (2013)
- Mills EJ, "Life expectancy of persons receiving combination antiretroviral therapy in low-income countries: a cohort analysis from Uganda", Ann Intern Med, 155, pp.209~216 (2011)
- Teeraananchai S, "Life expectancy of HIV-positive people after starting combination antiretroviral therapy: a meta-analysis", HIV Med, 18, pp.256~266 (2017)
- Harrison KM, "Life expectancy after HIV diagnosis based on national HIV surveillance data from 25 states, United States", J Acquir Immune Defic Syndr, 53, pp.124~130 (2010)
- Nsanzimana S, "Life expectancy among HIV-positive patients in Rwanda: a retrospective observational cohort study", Lancet Glob Health, 3, pp.e169~e177 (2015)
- Teeraananchai S, "Life expectancy after initiation of combination antiretroviral therapy in Thailand", Antivir Ther, 22, pp.393~402 (2017)
- Gueler A, "Life expectancy in HIV-positive persons in Switzerland: matched comparison with general population", AIDS, 31, pp.427~436 (2017)
- Mirzaei M, "Survival rate of AIDS disease and mortality in HIV-infected patients in Hamadan, Iran: a registry-based retrospective cohort study (1997-2011)", Int J STD AIDS, 24, pp.859~866 (2013)
- Chiang CL, "On constructing current life tables", J Am Stat Assoc, 67, pp.538~541 (1972)
- Stevens GA, "Guidelines for accurate and transparent health estimates reporting: the GATHER statement", PLoS Med, 13, pp.e1002056~ (2016)
- Alkema L, "Global, regional, and national levels and trends in maternal mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN Maternal Mortality Estimation Inter-Agency Group", Lancet, 387, pp.462~474 (2016)
- Mohammadi Y, "Measuring Iran’s success in achieving Millennium Development Goal 4: a systematic analysis of under-5 mortality at national and subnational levels from 1990 to 2015", Lancet Glob Health, 5, pp.e537~e544 (2017)
- "Life tables by country Iran (Islamic Republic of)"[URL]
- Poorolajal J, "Survival rate of AIDS disease and mortality in HIV-infected patients: a meta-analysis", Public Health, 139, pp.3~12 (2016)
- Poorolajal J, "Predictors of progression to AIDS and mortality post-HIV infection: a long-term retrospective cohort study", AIDS Care, 27, pp.1205~1212 (2015)
- Sabermahani A, "Provincial human development index, a guide for efficiency level analysis: the case of Iran", Iran J Public Health, 42, pp.149~157 (2013)
- "Incidence rate of tuberculosis in Iran"[URL]
- Sheidaei A, "National and subnational patterns of cause of death in iran 1990-2015: applied methods", Arch Iran Med, 20, pp.2~11 (2017)